摘要
目的：探讨艾滋病、结核病双重感染患者的临床治疗管理效果。方法选取本院2010年1月~2013年1月收治的艾滋病、结核病双重感染患者72例,均给予抗HIV治疗与抗结核治疗,通过1年随访观察患者的治疗效果。结果72例患者治疗后结核感染治疗有效共68例,总有效率为94.4%；2例患者未坚持抗HIV治疗,该治疗的依从性为97.2%。结核杆菌呈阴性与结核杆菌呈阳性患者治疗前后的CD4 T淋巴细胞计数差异均具有统计学意义（P〈0.05）。治疗结束后,4例患者发生过敏性皮疹,9例患者发生肝功能损害,纠正治疗后均获好转。结论对艾滋病与结核病双重感染的患者建立有效的治疗管理,能够保证早期诊治的正确开展,指导抗结核治疗与抗HIV治疗的联合应用,最终增加患者治疗依从性,提高临床施治效果,改善其生活质量,延长患者的生存时间。
Objective To investigate effect of clinical management of AIDS, tuberculosis co-infection. Methods Choosing 72 cases of patients who admitted to AIDS, tuberculosis co-infection in our hospital from January 2010 to January 2013 ,they were given anti-HIV therapy with anti-TB treatment, the treatment effect by 1-year follow-up observation of the patient.Results 72 patients effective treatment of tuberculosis infection treatment of 68 cases, total effective rate was 94.4%; 2 patients did not adhere to anti-HIV therapy , the treatment compliance was 97.2 %. Mycobacterium tuberculosis and Mycobacterium tuberculosis was negative -positive patients before and after treatment CD4 T lymphocyte count differences were statistically significant （P＆lt;0.05）. After the end of treatment, 4 patients allergic rash, 9 cases of liver damage in patients, were improved after corrective treatment.Conclusion The management team effective treatment for patients infected with both HIV and tuberculosis, to ensure the proper conduct of early diagnosis and treatment, guiding anti-TB treatment in combination with anti- HIV treatment, and ultimately increase patient treatment compliance and improve clinical and treatment effect, improve their quality of life and prolong survival time of patients.
出处
《中国现代药物应用》
2014年第8期32-33,共2页
Chinese Journal of Modern Drug Application
关键词
艾滋病
结核病
双重感染
治疗管理
AIDS
Tuberculosis
Dual infection
Treatment management
