摘要
目的:观察注射用长春西汀联合丹红注射液治疗后循环缺血综合征的疗效。方法:120例后循环缺血综合征患者随机分为观察组和对照组各60例,观察组在常规治疗基础上采用长春西汀20 mg加入0.9%氯化钠注射液250 ml,ivd,qd联合丹红注射液40 ml加入0.9%氯化钠注射液250 ml,ivd,qd;对照组在常规治疗基础上单用长春西汀20 mg加入0.9%氯化钠注射液250 ml,ivd,qd。疗程均为14 d。疗程结束后观察两组疗效,比较两组测定血液流变学指标和血流动力学指标。结果:观察组总有效率95.0%,明显高于对照组78.3%(P<0.05)。治疗后,两组血液流变学指标(高切黏度、低切黏度、血浆黏度、还原黏度)和TCD(LVA、RVA、BA、PI)均较治疗前明显改善(P<0.05),且观察组明显优于对照组(P<0.05)。结论:长春西汀联合丹红注射液治疗后循环缺血综合征的效果显著,可以有效改善血流变学和血流动力学的异常,值得临床推广及应用。
Objective：To observe the curative effect of vinpocetine combined with Danhong injections in the treatment of posterior circulation ischemia syndrome. Methods：Totally 120 patients with posterior circulation ischemia syndrome were selected and randomly divided into the treatment group and the control group with 60 cases in each. Both groups were treated by the conventional therapy, meanwhile, the treatment group was given vinpocetine and Danhong injections, and the control group was given vinpocetine alone. The treatment course was 14 days. The curative effect was observed, blood rheology and hemodynamics were also studied. Results：The to-tal effective rate of the treatment group was 95. 0%, which was significantly higher than that of the control group （75. 0%） with statis-tically significant difference（P〈0. 05）. After the treatment, the blood rheology （viscosity, low shear viscosity, plasma viscosity and reduced viscosity） and TCD （ LVA, RVA, BA and PI） in the two groups were significantly improved, and the treatment group showed more significant improvement（P〈0. 05）. Conclusion：Vinpocetine combined with Danhong injections in the treatment of posterior cir-culation ischemia syndrome has significant effect in the effective improvement of blood rheology and hemodynamics, which is worthy of clinical promotion and application.
出处
《中国药师》
CAS
2014年第4期627-629,共3页
China Pharmacist
关键词
长春西汀
丹红注射液
后循环缺血
疗效
血液流变学
血液动力学
Vinpocetine
Danhong injections
Posterior circulation ischemia
Curative effect
Blood rheology
Hemodynamics
