摘要
双相障碍临床表现复杂、病程多变,常导致临床识别不足、诊断不确定以及治疗困难。由此,学界开展了一系列研究,探索该病的特征与本质,并在循证医学的基础上践行有关诊断标准的修正以及治疗理念的纠正。该文从概念与诊断、神经生物学研究进展以及心境稳定剂治疗等方面对双相障碍的探索现状和前景进行评述。
Bipolar disorder is a common mental illness with complicated clinical features and variant depressive/ manic episode, resulting in under-recognition, misdiagnosis, and inappropriate treatment. Therefore, a series of researches have been carried out to explore its essential features and characteristics. Further more, diagnostic criteria and treatment principa/s have been modified based on the ~mdings from evidence-based medicine. This paper reviews the current researches on bipolar disorder and their prospects from perspectives such as concepts and diagnoses, neurobiology research progresses, as well as the mood stabilizers treatment.
出处
《上海交通大学学报(医学版)》
CAS
CSCD
北大核心
2014年第4期413-416,共4页
Journal of Shanghai Jiao tong University:Medical Science
基金
国家自然科学基金(91232719)
"十二五"国家科技支撑项目(2012BAI01B04)
国家临床重点专科-上海市精神卫生中心(卫生部医政司2011-873)~~
关键词
双相障碍
诊断
精神疾病诊断与统计手册
神经生物学
心境稳定剂
bipolar disorder
diagnosis
the diagnostic and statistical manual of mental disorders
neurobiology
mood stabilizer