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韦格纳肉芽肿1例误诊分析

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摘要 患者,女,36岁.主诉发热、咳嗽、鼻塞2月,加重伴胸闷、气短、听力下降10d.2个月前患者无明显诱因的出现发热、咳嗽、鼻塞症状,伴有结膜充血,患者遂到当地医院就诊,查胸部CT示(图1):多发性结节,结核?结节病?给予抗炎对症治疗,症状未见明显缓解,来我院做气管镜提示:气管及左右支气管可见散在的大小不等的黄白色结节,黏膜充血水肿,当时诊断为“结节病”,给予糖皮质激素治疗,症状明显好转,查胸部CT较前明显好转(图2);出院给予,泼尼松每天50mg,口服治疗,到当地医院继续治疗,入院前10d上述症状加重,并出现胸闷,气短,乏力,听力减退,伴有鼻腔出血,在当地医院做胸部、鼻窦CT提示病变加重(图3),累及左侧鼻窦(图4),随来我院以“韦格纳肉芽肿?”收住.体检:结膜充血,睑结膜有小结节,表面充血,鼻腔内可见浓性分泌物,填塞鼻腔,通气障碍,双肺呼吸音低,无明显的干湿性啰音,右手拇指、示指可见小结节.
出处 《临床合理用药杂志》 2014年第11期126-127,共2页 Chinese Journal of Clinical Rational Drug Use
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  • 1Casper FM, Franssen Coen A, Stegemem Cees GM, et al. Antiproteinase-3 and antimyeloperoxidase-associated vasculitis[J]. Kidney International,2000,57(6) :2195.
  • 2Alpa M,Ferrero B, Cavallo R, et al. Anti-GML and anti-sulphatide antibodies in systemic idiophatic vasculitis,systemic lupus erythematosus and mixed cryoglobulinaemia: serum detection and clinical and electrophysiologic correlations[J]. G Ital Nefrol, 2002,19(6) :617.
  • 3Franssen CF, Huitema MG, Muller kobold AG,et al. Invitro neutrophil activation by antibodies to protemase 3 and myeloperoxidase from patients with crescentic glomerulonephritis[J]. J Am Soc Nephrol, 1999,10(7):1506.
  • 4David R Ralston,Clay B Marsh, Meliesa P Lowe,et al. Antineutrophil cytoplasmic antibodies induce monocyte IL-8 release: Role of surface proteinase-3,alphal-autitrypsin,and Fc gamma receptors[J] .J Clin Invest,1997, 100:1416.
  • 5Muller kobold AC, van Wijk RT, Franssen CFM, et al.In vitro up-regulation of E-selection and induction of interleukin-6 in endothelial cells by autoantibodies Wegener's granulomatosis and microscopic polyangiitis[J] .Clin Exp Rheumatol ,1999,17:433.
  • 6Tomer Y, Liter O, Gilburd B, et al. Anti-neutrophil cytoplasmic antibody-enriched IgG induces adhesion of human T lymphocytes to extracellular matrix proteins[J] .Clin Immunol Immunopathol, 1997,83(3):245.
  • 7Savige J,Nassis L, Cooper T, et al. ANCA-associated systemic vasculitis after immunization with bacterial proteins[J]. Clin Exp Rheumatol, 2002,20(6):783.
  • 8Falk RT, Nachman PH, Hogan SL, et al. ANCA glomerulonephritis and vasculitis:a Chapel Hill perspective[J]. Semin-Nephrol,2000,20(3):233.
  • 9Vizjak A. Nagode B, Rott T, et al. Antineutrophil cytoplasmic autoantibodies-antigen specificity and associated diseases[J]. Wire Klin Wochen-schr,2000,112(15-16) :665.
  • 10Bartunkova J,Janatkova I,Tesar V,et al.The spectrum of disease associated with antineutrophil cytoplasmic antibodies[J].Cas Lek Cesk,1995,134(1):18.

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