摘要
目的探讨腹腔镜下与开腹全子宫切除术对中青年女性卵巢功能的影响。方法选择60例未绝经的子宫良性疾病并需行子宫切除术的中青年患者,随机分为腹腔镜组和开腹组,每组各30例,比较两组患者围手术期指标、性激素水平及围绝经期综合征情况。结果腹腔镜组术中出血量、术后肛门排气时间均显著少于开腹组,差异有统计学意义(t值分别为4.27和3.11,P<0.05);术后6个月,两组患者卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E_2)、孕酮(P)水平相比,差异均无统计学意义(t值分别为0.69、0.95、0.67、-0.33,均P>0.05);术后12个月两组患者FSH、LH、E_2、P水平差异也均无统计学意义(t值分别为0.88、-0.21、1.65、0.20,均P>0.05);两组患者术后围绝经期综合征发生率比较差异无统计学意义(x^2=0.10,P>0.05)。结论腹腔镜子宫切除术具有对机体创伤小、术后恢复快的优点,与传统子宫切除术相比不会增加对卵巢功能的损伤。
Objective To investigate the effect of laparoscopic hysterectomy （ LH） and abdominal hysterectomy （ AH） on ovarian function of young and middle-aged women.Methods Totally 60 young and middle-aged premenopausal patients with benign uterine disease were going to undergo hysterectomy .They were randomly divided into LH group and AH group with 30 cases in each .The perioperative indexes , sexual hormone level and perimenopausal syndrome were compared between two groups .Results The blood loss and postoperative flatus in LH group were significantly less than AH group , and the differences were significant （t value was 4.27 and 3.11, respectively, both P〈0.05）.The serum levels of FSH, LH, E2 and P were not significantly different between two groups in 6 months after surgery （t value was 0.69, 0.95, 0.67 and -0.33, respectively, all P〉0.05）.There were not significant differences in the serum levels of FSH , LH, E2 and P in 12 months after surgery （ t value was 0.88, -0.21, 1.65 and 0.20, respectively, all P〉0.05 ）.The incidence of perimenopausal syndrome was not significantly different between two groups （χ2 =0.10,P〈0.05）.Conclusion With the advantages of mild trauma and rapid recovery , laparoscopic hysterectomy does not increase the damage to ovarian function .
出处
《中国妇幼健康研究》
2014年第2期263-265,共3页
Chinese Journal of Woman and Child Health Research
关键词
腹腔镜
子宫切除术
中青年女性
卵巢功能
laparoscopy
hysterectomy
young and middle-aged women
ovarian function
