摘要
目的探讨罗哌卡因复合舒芬太尼蛛网膜下腔麻醉在剖宫产手术的应用效果。方法将110例拟行剖宫产手术产妇采用数字表法随机分为两组,每组各55例,对照组采用罗哌卡因蛛网膜下腔麻醉,观察组采取罗哌卡因复合舒芬太尼蛛网膜下腔麻醉,观察两组麻醉起效时间、镇痛维持时间、术后视觉模拟评分法(VAS)及新生儿1min、5min Apgar评分,比较两组不良反应发生情况。结果观察组麻醉起效时间为(56.54±4.51)s,少于对照组的(83.36±4.85)s,t=6.53,P<0.05;镇痛维持时间和术后VAS评分为(5.21±0.42)h和(1.38±0.20)min,高于对照组的(3.45±0.31)h和(3.35±0.42)min,两组比较差异均具有统计学意义(t值分别为5.21和8.20,均P<0.05);两组新生儿1 min、5 min Apgar评分及不良反应发生率比较均无显著性差异(t值分别为1.62和1.35,x^2=1.09,均P>0.05)。结论罗哌卡因复合舒芬太尼蛛网膜下腔麻醉用于剖宫产手术具有较好的镇痛效果,且镇痛起效快、维持时间长、不良反应少,具有较好的临床应用价值。
Objective To investigate the effect of subarachnoid anesthesia with ropivacaine and sufentanil in cesarean surgery .Methods Totally 110 cases of women who would undergo cesarean were divided into two groups by using random number table with 55 cases in each group.The control group was given ropivacaine spinal anesthesia , while the observation group was given ropivacaine and sufentanil in subarachnoid anesthesia .Onset time of anesthesia, analgesia duration, postoperative VAS score and neonatal 1min, 5 min Apgar score were observed and the adverse events of two groups were compared .Results The onset time of anesthesia of the observation group was 56.54 ±4.51 s, which was significantly less than the control group （83.36 ±4.85s） （t=6.53,P〈0.05）.Its analgesia duration and postoperative VAS score was 5.21 ±0.42 h and 1.38 ±0.20 min, respectively, which were significantly higher than the control group （3.45 ±0.31 h and 3.35 ±0.42 min）.The differences were statistically significant （t value was 5.21 and 8.20, respectively, both P〈0.05）.The two groups were not significantly different in neonatal 1min, 5 min Apgar score and the incidence of adverse reactions （t value was 1.62 and 1.35, respectively,χ2 =1.09,P〈0.05）.Conclusion Ropivacaine combined with sufentanil in subarachnoid anesthesia has better analgesic effect and rapid onset of analgesia .The analgesia duration is long , and the adverse reactions are few with better clinical value.
出处
《中国妇幼健康研究》
2014年第2期297-299,共3页
Chinese Journal of Woman and Child Health Research
关键词
罗哌卡因
舒芬太尼
麻醉
剖宫产
ropivacaine
sufentanil
anesthesia
cesarean section
