摘要
目的观察腹腔镜手术与开腹手术治疗妇科急腹症的疗效及其对C反应蛋白(CRP),前白蛋白(PA)和降钙素原(PCT)的影响。方法选择海盐县妇幼保健院2012年1月至2013年1月妇科急腹症患者120例,分为腹腔镜组和开腹组,每组各60例。观察两组患者的手术时间、术中出血量、肛门排气时间、视觉模拟评分(VAS评分)、住院时间、并发症发生率及治疗前后PA、PCT和CRP水平变化。结果腹腔镜组的手术时间、术中出血量、肛门排气时间、VAS评分、住院时间和术后并发症发生率较开腹组明显缩短或减少,差异有统计学意义(t值分别为8.331、13.779、10.696、11.480、6.688、3.962,均P<0.05)。治疗前两组的CRP、PCT和PA水平差异无统计学意义(t值分别为0.671,0.476,0.854,均P>0.05),治疗后两组的CRP和PCT水平均较治疗前显著降低(t值分别为33.922、45.316、30.947、35.258,均P<0.01),而两组治疗后PA水平较治疗前显著升高(t值分别为8.099、6.315,均P<0.01)。治疗后腹腔镜组与开腹组相比,CRP和PCT水平降低更为明显,且差异有统计学意义(t值分别为8.184、21.775,均P<0.01),而PA水平升高更为明显,且差异有统计学意义(t=2.447,P<0.01)。结论腹腔镜手术是治疗妇科急腹症的一种理想、安全、可靠的术式,具有创伤小,恢复快等优点。
Objective To compare the efficacy of laparoscopic surgel7 and open surgery on the treatment of gynecological acute abdominal diseases and their impacts on C-reactive protein （ CRP）, procalcitonin （PCT） and prealbumin （PA）. Methods Totally 120 patients with gynecological acute abdominal diseases admitted in Women and Children Health Care Hospital of Haiyan during the period of January 2012 to June 2013 were divided into laparoscopic group and laparotomy group with 60 cases in each group. The operative time, blood loss, flatus time, visual analog scale （VAS） score, hospitalization time and incidence of complication were observed in two groups, and the levels of PA, PCT and CRP were detected before and after treatment. Results The operative time, blood loss, flatus time, VAS score, hospitalization time and incidence of complication were significantly reduced in laparoscopic group than in laparotomy group （ t value was 8.331, 13.779, 10.696, 11.480, 6.688 and 3. 962, respectively, all P 〈0.05）. There were no significant differences in CRP, PCT and PA between two groups before treatment （t value was 0. 671, 0. 476 and 0. 854, respectively, all P 〉 0.05 ）. After treatment, the CRP and PCT levels in two groups were significantly lower than those before treatment （t value was 33. 922, 45. 316, 30.947 and 35. 258, respectively, all P 〈 0.01 ）. Whereas, the PA levels in two groups were significantly higher than those before treatment （ t value was 8. 099 and 6. 315, respectively, both P 〈 0.01 ）. Compared with laparotomy group, the levels of CRP and PCT in laparoscopic group decreased more obviously after treatment （t value was 8. 184 and 21. 775, respectively, both P 〈 0.01 ）, and the level of PA increased more obviously （ t = 2. 447, P 〈 0.01 ）. Conclusion Laparoscopic surgery is an ideal treatment for gynecological acute abdominal diseases. It is a safe and reliable procedure for mild trauma and quick recovery.
出处
《中国妇幼健康研究》
2014年第2期308-310,共3页
Chinese Journal of Woman and Child Health Research
关键词
腹腔镜手术
妇科急腹症
C反应蛋白
前白蛋白
降钙素原
laparoscopic surgery
gynecological acute abdominal disease
C-reactive protein （CRP）
prealbumin （PA）
procalcitonin（PCT）
