摘要
目的 :揭示醒脑开窍针刺法治疗脑梗塞的分子机制。方法 :采用分子杂交的技术 ,观察了实验性脑梗塞大鼠缺血区脑组织HSP70 mRNA的转录水平 ,并观察了醒脑开窍针刺法对缺血区脑组织HSP70 mRNA表达的干预作用。 结果 :发现醒脑开窍针刺法可增加梗塞区皮质、纹状体、海马HSP70 基因的表达。证实了醒脑开窍针刺法对缺血后的脑细胞的保护作用优于常规针刺法 。
Purpose To explore molecular mechanism of Xingnao Kaiqiao needling method for treatment of cerebral infarction.Methods Molecular hybridization techniques were used to observe the transcription level of HSP 70 mRNA in the cortex,striatum and hippocampus in rats of middle cerebral artery obstruction,and the effect of Xingnao Kaiqiao needling method on HSP 70 mRNA expression.Results Xingnao Kaiqiao needing method increased HSP 70 mRNA expression.Conclusion Xing nai Kai qiao needling method has a better protective action than that of routine needling method on brain cells after ischemia. [
出处
《中国针灸》
CAS
CSCD
北大核心
2001年第2期107-112,共6页
Chinese Acupuncture & Moxibustion
基金
天津市 2 1世纪---青年科学基金资助项目!编号 :983 70 3 111
关键词
脑梗塞
针灸疗法
醒脑开窍
热休克蛋白
基因表达
Cerebral Infarction/acup ther
Consciousness Restor Resuscitat
Heat Shock Protein/metab
