摘要
目的提高人们对类鼻疽临床特征及该病严重危害人民生命健康的认识。方法收集从2009年3月至2012年2月经各种标本培养(血、痰、尿、胸水、心包积液、脓液及分泌物等)证实的40例类鼻疽患者为研究对象,探讨其临床特征;并通过8个月至3.5年的随访,了解其复发率及病死率。结果类鼻疽患者居住地主要来源于海南岛沿海市县,位于海南岛西边的东方市患者例数最多(9例),而位于岛屿中心的县市患者为极少数。临床表现主要为类鼻疽肺炎40%、泌尿系感染17.5%、皮肤软组织感染15%及消化系统感染(肝、脾脓肿形成)12.5%。包括出院后随访结果统计显示,类鼻疽复发率和总病死率均为15%。结论类鼻疽临床表现多样化,各系统均可能累及,容易误诊。随访发现存在高复发率及高病死率,尽管如此,和国内之前报道的病死率(36.8%)相比,病死率有明显下降。
Objective To raise awareness of the clinical features of melioidosis as being severely harmful to human health. Methods It was collected that 40 cases with culture-proven melioidosis from May 2009 to February 2012, to retrospectively analyzed for clinical characteristics in Hainan island. And by 8 months to 3.5 years of follow-up to reveal the recurrence rate and mortality rate. Results Most of the patients lived around Hainan island. The main clinical manifestations included pneumonia 40%, genitourinary infection 7.5%, skin and soft tissue infection 15%, liver and/or splenic abscesses 12. 5%. Follow-up outcomes revealed that the recurrence rate and overall mortality rate were both 15%. Conclusions The wide range of clinical presentations of melioidosis can lead to frequent misdiagnosis. High recurrence rate and overall mortality rate were found through follow-up. Neverthless, mortality rate decreased significantly compared to previous data （36.8%）.
出处
《中华肺部疾病杂志（电子版）》
CAS
2014年第2期55-57,共3页
Chinese Journal of Lung Diseases(Electronic Edition)
关键词
海南岛
类鼻疽
类鼻疽伯克霍尔德菌
临床随访
Hainan island
Melioidosis
Burkholderia pseudomallei
Clinnical follow-up
