摘要
IgA血管炎(IgAvasculitis,IgAV)与IgA肾病(IgAnephropathy,IgAN)免疫病理均显示为IgA沉积,且IgAl分子糖基化异常是其共同主要的发病机制。因此,究竟两者是不是同一种疾病,临床上一直存在争议。现就病因、流行病学、临床、病理、发病机制及预后等方面来分析二者异同。
The immunopathogenesis of IgA vasculitis and IgA nephropathy both demonstrate IgA deposition, and abnormal glycosylation of IgA1 molecule is their major pathogenesis. Therefore, it is clinically controversial that they are actually one disease. The present text will delineate their similarities and differences from aspects of epidemio- logy, clinic, pathology , mechanism and prognosis.
出处
《中华实用儿科临床杂志》
CAS
CSCD
北大核心
2014年第9期653-654,共2页
Chinese Journal of Applied Clinical Pediatrics