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去甲基化药物地西他滨治疗血液系统恶性肿瘤的研究进展 被引量:10

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摘要 随着对恶性血液肿瘤发生机制的表观遗传学研究的不断深入,发现DNA异常甲基化在恶性血液肿瘤的发生、发展中起着重要的作用。地西他滨是一种去甲基化药物,具有抑制甲基化转移酶的作用,对血液性恶性癌变及实体瘤具有广谱抗肿瘤活性,在上述肿瘤的治疗中取得了良好的疗效。
作者 李娜 侯丽虹
出处 《中国医药科学》 2014年第6期44-48,58,共6页 China Medicine And Pharmacy
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