摘要
目的优选抗痨清肺颗粒的最佳提取工艺。方法以岩白菜素提取转移率、总多糖浸出率、浸膏得率为评价指标,采用正交试验设计考察浸泡时间、加水量、提取时间对提取工艺的影响。结果抗痨清肺颗粒的最佳提取工艺条件为:加水浸泡1.0 h,回流提取2次,加水量分别为10、8倍量,提取时间分别为2.5、2.0 h。结论优选出的提取工艺简单、稳定,可为抗痨清肺颗粒的工业化生产提供依据。
Objective To optimize the extraction process of Kanglao Qingfei granules. Methods Orthogonal test design was used to study the influence of soaking time, water content, extraction time on extraction technology with bergenin＆#39;s extraction rate, total polysaccharides＆#39;s extraction rate and extract yield as evaluation indexes. Results The optimum extraction process conditions were as follows：the raw materials were immersed in water for 1.0 h and extracted two times under reflux, and the ratio of water volume to raw materials weight was 10 and 8 （mL/g）, and extraction time was 2.5 h and 2.0 h, respectively. Conclusion The optimized extraction process was simple and stable, which can provide foundation for industrial production of Kanglao Qingfei granules.
出处
《中国中医药信息杂志》
CAS
CSCD
2014年第5期91-94,共4页
Chinese Journal of Information on Traditional Chinese Medicine
基金
国家科技重大专项-艾滋病和病毒性肝炎等重大传染病防治(2013ZX10005004-003)
关键词
抗痨清肺颗粒
正交试验
提取工艺
岩白菜素
多糖
Kanglao Qingfei granules
orthogonal test
extraction technology
bergenin
polysaccharide
