摘要
目的了解本地区就诊患者分枝杆菌感染状况和结核分枝杆菌耐药情况。方法用对患者标本进行分枝杆菌培养鉴定和药敏试验。结果 9653份标本分枝杆菌培养阳性2759例,其中1229株分枝杆菌行菌种鉴定和药敏试验,非结核分枝杆菌219株,结核分枝杆菌1010株,纳入929株药敏结果进行分析,对4种一线抗结核药物至少耐一药232株,耐二药51株、耐三药49株,耐四药33株,耐多药92株。结论本地区分枝杆菌非肺部感染应引起高度重视,结核菌总耐药率和耐多药率近几年维持在稳定高位,结核菌耐药情况仍然十分严重。
Objective To explore the infectious status of mycobacterium and drug resistance of mycobacteri-um tuberculosis （ MTB） . Methods The samples were cultured to give drug sensitivity test. Results 2759 positive strains of mycobacterium were isolated within 9653 samples, 1229 of which were identified and given susceptibility test. There were 219 strains of non-tuberculous mycobacteria, and 1010 strains of tuberculosis mycobacteria. The phenotype drug susceptibility of 929 strains were analyzed, which found that 232 strains resistant to at least one drug, 51 strains to two drugs, 49 strains to three drugs, 33 strains to four drugs, and 92 strains of MDR. Conclusion Non-pulmonary tuberculosis should be given a sufficient attention in addition to pulmonary mycobacterial infection. The overall resistance of TB and MDR remains at a steady high level in recent years in Shenzhen area, and the situa-tion is still very serious for drug-resistant TB.
出处
《临床肺科杂志》
2014年第6期1046-1048,共3页
Journal of Clinical Pulmonary Medicine
基金
深圳市科技研发资金项目(No:JCYJ20130401164749996)
关键词
结核分枝杆菌
药敏试验
耐多药结核
耐药率
mycobacterium tuberculosis
drug susceptibility test
multidrug resistant tuberculosis
drug re-sistance
