摘要
目的探讨血清TSH水平对分化型甲状腺癌(DTC)首次131I清甲疗效的影响。方法选择DTC患者248例,行常规131I治疗,治疗前查血清TSH,治疗后4~6个月随访,对比不同TSH水平下131I清甲成功率的高低。结果本组248例中TSH≥30 mU/L者118例,首次131I治疗清甲成功率为54.2%;TSH<30 mU/L者130例,清甲成功率为28.5%;清甲成功101例与为未成功147例的TSH均值差异有统计学意义(P<0.01)。结论 131I治疗前血清TSH水平是影响DTC首次131I清甲效果的重要因素。TSH水平越高,一次清甲的成功率越高。
Objective To investigate the influence of thyroid stimulating hormone （TSH） levels on the efficacy of the first 131I thyroid ablation for differentiated thyroid cancer （DTC）. Methods The 248 patients with DTC in 131I treatment were selected. All patients were detected the TSH values before J3q treatment and were followed-up after 131I treatment of 4-6 months. The 131I thyroid ablation success rates between the groups with high and with low levels of TSH were compared. Results Among 118 cases with TSH≥30mU/L,the first time 131I thyroid ablation success rate was 54.2%. Among 130 cases with TSH〈30 mU/L,the success rate was 28.5%（P〈 0.01）. The average value of TSH was compared between the 101 cases with suceessful thyroid ablation and 147 cases with non successful thyroid ablation （51.44±41.04 vs 30.83±36.09 mU/L,t=4.177,P〈0.01）. Conclusion The TSH value is an important factor to the first time 131I thyroid ablation effect of patients with DTC. The higher TSH value is the higher ablation success rate is.
出处
《实用医药杂志》
2014年第4期298-300,共3页
Practical Journal of Medicine & Pharmacy
关键词
促甲状腺素(TSH)
分化型甲状腺癌
131I治疗
清甲
Thyroid stimulating hormone （TSH）
Differentiated thyroid cancer （DTC）
131I treatment
Thyroid ablation
