摘要
目的了解某部队医院患者医院感染多重耐药菌分布及耐药性变化趋势,指导临床合理用药。方法采用临床标本病原学检测和药敏试验方法,对解放军某部医院住院患者送检标本进行检测与分析。结果该医院在2011年度从患者送检标本中共分离出多重耐药菌643株,占医院感染病原菌总数的22.5%。多重耐药菌种类主要有大肠埃希菌、铜绿假单胞菌、金黄色葡萄球菌和肺炎克雷伯菌,构成比依次为30.33%、24.73%、12.60%和10.58%。革兰阴性多重耐药菌对头孢哌酮/舒巴坦和亚胺培南有较高敏感性,金黄色葡萄球菌对万古霉素高度敏感。结论多重耐药菌已成为医院感染的重要病原菌,需要加强对多重耐药菌的监控,以控制其传播与形成。
Objective To investigate the distribution and the tendency of muhidrug - resistant organism infections in mil- itary hospitals, so as to suggest rational use of drug. Methods The etiological examinations and drug sensitive tests were used to examine and analyze samples of in - patients in our hospital in the year of 2011. Results Totally 643 strains of muhidrug- resistant organism were separated, which accounted for 22. 5% of the nosocomial infection pathgeon. Esche- richia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Klebsiella pneumoniae occupied 30. 33%, 24.73%, 12. 60%, and 10. 58% in these bacteria respectively. The Gram - negative muhidrug - resistant organism was more sensi- tive to the cefoperazone/sulbactam, while the Staphylococcus aureus was more sensitive to the vancomycin. Conclusion Muhidrug - resistant organism has become one of the most important pathogenic bacteria in nosocomial infection. It is es- sential to enhance its bacterial monitor, so as to control its formation and spread.
出处
《中国消毒学杂志》
CAS
北大核心
2014年第4期363-365,369,共4页
Chinese Journal of Disinfection
关键词
多重耐药菌
医院感染
耐药性
监测
multidrug - resistant organism
nosocomial infection
drug resistance
bacterial monitor
