摘要
目的探讨国内致心律失常性右室心肌病（ARVC）的发病现状、临床特征和诊治情况。方法在CNKI、万方数据库、维普数据库、Pubmed中以“ARVC／D”为自由词或关键词，检索国内1986～2008年发表的ARVC病例42例。采用回顾性方法，对资料进行汇总分析。结果ARVC患病率男女比为3．2：1；首发症状年龄为（31．3±13．2）岁，3例有家族猝死史，均为兄弟关系。心悸为最常见症状（73．2％），其次为晕厥（56．1％）。52．0％患者心界扩大，32例（76．2％）出现室性心动过速，Epsilon波检出率为38．1％。33例（78．6％）患者超声心动图提示右室增大，右室壁瘤样膨出占31．0％（13例）。5例进行了右室心肌活检，全部有不同程度的心肌脂肪浸润、心肌纤维化等改变。23例使用抗心律失常药物治疗，3例患者抗心律失常药物＋室性心动过速射频消融治疗，仅1例安装埋藏式心脏转复除颤器（ICD）。结论国内ARVC患者以中青年多见，男性多于女性，晕厥、心悸为常见症状，可见多种心律失常，形态学异常以右室扩大、右室瘤样膨出较常见；ICD植入率低。
Objective To find out the onset status, clinical features, diagnosis and treatment informations of arrhythmogenic right ventricular cardiomyopathy （ARVC） in China. Methods between January 1986 and December 2008, 42 patients found from the cases reported in China with ＂ARVC/D＂ as the free word or keyword in the databases of CNKI, WAN FANG, VIP and Pubmed at the same time. Review all the related information of the eligible patients and cases in literatures. Results The ratio of men to women of ARVC was 3.2 to 1. The age was （ 31.3± 13.2 ） years at the time on admission. Three patients had family history of sudden death, and all of them were brothers. The most common complaint was palpitation （73.2%） with syncope as the second common symptom （56.1%）. 15 （52.0%） patients suffered from expansion of cardiac border. Ventricular arrhythmia was most common as seen in 32 cases （76.2%）. The specific Epsilon waves were found in 38.1% （ n= 16） cases. The most common finding was expansion of right cardiac ventricle （78.6%） , and Aneurysm-like extrusion of the right ventricle accounted for 31.0%. Myocardial biopsies were performed in 5 patients. All of them showed myocardium fatty infiltration of various degrees and myocardial fibrosis. 23 patients were treated with antiarrhymthic drugs only. Three patients received antiarrhymthic drugs and ablation of ventricular tachycardia. Only one patient was implanted with ICD. Conclusion Patients with ARVC in China can be more often seen in young people with the common symptoms of syncope and palpitation. A variety of arrhythmias can be seen. The abnormal conditions of morphology include the expansion of right ventricle and aneurysm-like extrusion of right ventricle. The implantation rate of ICD is low.
出处
《中国心脏起搏与心电生理杂志》
2014年第2期132-135,共4页
Chinese Journal of Cardiac Pacing and Electrophysiology
关键词
心血管病学
致心律失常性右室心肌病
心肌疾病
病例分析
Cardiology
Arrhythmogenic right ventricular cardiomyopathy
Myocardium disease
Analysis of cases
