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成纤维样滑膜细胞Toll样受体在类风湿性关节炎的研究进展 被引量：5

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摘要 Toll样受体（toll-like receptor，TLRs）是一种I型跨膜蛋白受体，可识别微生物上特定结构的病原相关分子模式（pathogen-associated molecular patterns，PAMPs）和宿主自身损伤细胞产生的损伤相关分子模式（damage-associated molecular patterns，DAMPs），在天然免疫中发挥着重要作用。
作者 唐媚 胡松 唐信威 刘阳 王衍堂 邹强
机构地区 遵义医学院免疫学教研室 成都医学院免疫学教研室
出处 《成都医学院学报》 CAS 2014年第2期217-221,共5页 Journal of Chengdu Medical College
基金 国家自然基金资助项目(NO:81273530 81202363 81302786)
关键词 类风湿性关节炎 TOLL样受体 成纤维样滑膜细胞
分类号 R392.9 [医药卫生—免疫学]
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参考文献34

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同被引文献118

  • 1李国莺,章维志,姜璐,陈光亮.萆薢总皂苷对尿酸钠诱导THP-1细胞Toll样受体/核转录因子-κB(TLR/NF-κB)信号通路的影响[J].中国实验方剂学杂志,2020,0(5):34-41. 被引量：31
  • 2Souza JA, Rossa C Jr, Garlet GP, et al. Modulation of host cell signaling pathways as a therapeutic approach in periodontal disease[ J ]. J Appl Oral Sei, 2012, 20(2) : 128 -138.
  • 3Iwai K. Diverse roles of the ubiquitin system in NF-KB activation [ J]. Biochim Biophys Acta, 2014, 1843 ( 1 ) : 129 - 136.
  • 4I-Ianyecz A, Olasz k, Tarjanyi O, et al. Protcoglycan aggecan conducting T cell activation and apoptosis in a murine model of rheumatoidarthritis[ J/OL]. Biomed Res Int, 2014, 2014 : 942148.
  • 5Smith HS, Smith AR, Seidner P. Painful rheumatoid arthritis [ J ]. Pain Physician, 2011, 14 (5) : E427 - E458.
  • 6Min SY, Yan M, Du Y, et al. Intra-articular nuclear factor-B blockade ameliorates collagen-induced arthritis in mice by eliciting regulatory T cells and maerophages[ J]. Clin Exp Immunol, 2013, 172(2) : 217 -227.
  • 7Guo X, Pan Y, Xiao C, et al. Fractalkine stimulates cell growth and increases its expression v/a NF-KB pathway in RA-FLS [ J]. Int J Rheum Dis, 2012, 15(3) : 322 -329.
  • 8Lee HS, Woo S J, Koh HW, et al. Regulation of apoptosis and inflammatory responses by insulin-llke growth factor binding protein 3 in fibroblast-like synoviocytes and experimental animal models of rheumatoid arthritis [ J ]. Arthritis Rheumatol, 2014, 66 ( 4 ) : 863 - 873.
  • 9Lin TH, Yang RS, Wang KC, et al. Ethanol extracts of fresh DavaUia formana ( WL1101 ) inhibit osteoclast differentiation by suppressing RANKL-induced nuclear factor-kappa B activation [ J/OL ]. Evid Based Complement Alternat Med, 2013, 2013: 647189.
  • 10Mediero A, Perez-Aso M, Cronstein BN. Activation of adenosine A (2A) receptor reduces osteoclast formation via PKA- and ERK1/2- mediated suppression of NF-KB nuclear translocation [ J ]. Br J Pharmacol, 2013, 169(6) : 1372 - 1388.

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成都医学院学报
2014年 第2期

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