摘要
UBX(泛素调控X因子)蛋白质家族在泛素化相关的过程中起着重要的作用,如细胞周期调控、转录调控、信号转导、发育、胁迫响应、细胞程序性死亡、内吞作用和DNA修复。然而,到目前为止,UBX家族在杨树和葡萄中还没有被研究过。为了更好的弄清这两个植物的UBX家族,我们对UBX的基因结构、染色体位置、基因重复、系统发育关系作了分析。该研究对葡萄和杨树的UBX蛋白质家族作了第一个系统的分析。基因的外显子/内含子结构和蛋白质基序组成在同一个组里相对比较保守。基因重复分析表明,串联重复和片段重复对于杨树和葡萄的UBX基因家族的扩张有一定贡献,基因缺失在UBX基因家族的扩张过程中也发生了作用。本研究为UBX蛋白质功能的研究奠定了基础。
The UBX （Ubiquitin regulatory X） protein family plays important roles in ubiquitin-related processes including cell-cycle control, transcriptional regulation, signal transduction, development, stress response, programmed cell death, endocytosis and DNA repair. However, this family has not been studied to date in Poptdus and Vitis. To better understand the UBX in these two plants, relevant analyses about gene structure, chromosomal location, duplication, phylogenetic relationships were performed. Our study provides the first systematic analysis of the Vitis and Populus UBX proteins. The exon/intron gene structure and motif composition were relatively conserved in the same group. Duplication analyses suggested that tandem duplication and segmental duplication contribute to the expansion of Populus and Vitis UBX gene family, while some gene loss has also occurred. The results presented basic information on UBX proteins, which may show a scaffold for future functional analysis of this family.
出处
《植物分类与资源学报》
CAS
CSCD
北大核心
2014年第3期349-357,共9页
Plant Diversity
基金
The"Strategic Priority Research Program"of the Chinese Academy of Sciences (XDA05050206)
