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Survivin、PCNA在子宫肌瘤中的表达及相关性研究 被引量:5

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摘要 目的探讨Survivin与PCNA在子宫肌瘤的表达和意义及相关性。方法用免疫组化S-P法检测30例正常子宫肌层组织和30例子宫肌瘤组织中Survivin与PCNA蛋白的表达情况。结果 Survivin在子宫肌瘤组织中的阳性率明显高于正常子宫肌层组织,(χ2=7.576,P=0.006),PCNA在子宫肌瘤组织的阳性率明显高于正常子宫肌层组织(χ2=7.576,P=0.006),在子宫肌瘤组织Survivin与PCNA的表达呈正相关性(r=0.779,P=0.000)。结论子宫肌瘤组织中Survivin与PCNA可能在细胞的增殖中发生协同作用,共同参与子宫肌瘤的发生发展。
作者 王芳
机构地区 株洲市中心医院
出处 《中国医药指南》 2014年第14期83-84,共2页 Guide of China Medicine
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参考文献6

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