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PCI术中血栓抽吸联合替罗非班对急性ST段抬高型心肌梗死的疗效观察 被引量：4

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摘要 目的观察PCI术中血栓抽吸联合替罗非班在急性ST段抬高型心肌梗死(STEMI)患者中的疗效。方法 2010年8月至2012年8月住院治疗的急性STEMI患者118例,随机分为观察组(PCI+血栓抽吸联合替罗非班)62例和对照组(直接PCI)56例。观察PCI术后即刻TIMI血流分级、无复流发生率、球囊使用率、支架置入率、ST段回落率、肌钙蛋白T(TnT)峰值和肌酸激酶同工酶(CK-MB)峰值、左心室射血分数(LVEF)、6个月内主要心血管不良事件(MACE)的发生率。结果与对照组比较,观察组术后TIMI 3级血流发生率明显增高(P<0.01),无复流发生率明显减少(P<0.01),球囊使用率明显降低(P<0.01),两组支架植入率相当(P>0.05)。与对照组比较,观察组的TnT及CK-MB峰值显著降低(P均<0.01),心电图的ST段回落率、LVEF值明显增加(P<0.01,P<0.05),6个月内的心衰发生率、再次AMI发生率显著降低(P<0.01,P<0.05)。结论 PCI术中血栓抽吸联合替罗非班能明显降低急性STEMI患者冠脉内血栓负荷,改善冠脉血流,减小梗死面积,改善患者的预后。
作者 王大强
机构地区 河南省南阳医学高等专科学校第一附属医院心内科
出处 《中国临床研究》 CAS 2014年第5期539-540,共2页 Chinese Journal of Clinical Research
关键词 急性心肌梗死 ST段抬高型 经皮冠状动脉介入术 血栓抽吸 替罗非班
分类号 R542.22 [医药卫生—心血管疾病]
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共引文献33

同被引文献51

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中国临床研究
2014年 第5期

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