摘要
目的分析姑息减压手术应用于老年脊柱转移瘤中的临床疗效和生存率。方法根据患者预生存期以及一般身体情况选择行姑息减压手术的为观察组,行肿瘤切除手术为对照组,比较患者术后的临床疗效、视觉模拟评分法(VAS)评分、Frankel分级、ECOG评分,采用Kaplan-Meier法对患者的生存率进行评估。结果观察组术前存在脊髓功能障碍的患者术后81.5%Frankel分级有改善,对照组为80.0%,两组发生神经功能恶化的例数分别为18例与10例,中位时间为6个月与13个月。结论姑息减压术手术时间短、术中出血量少、并发症较少、手术风险少,对于一般情况较差,预估生存期小于半年的老年脊柱转移瘤患者是一种有价值的治疗方法。
Objective To analyze the clinical effectiveness and survival rate of applying palliative decompression operation to elderly patients with spinal metastasis.Methods The patients were divided into experimental group and control group based on the preliminary lifetime and general situation of the patients.The patients in experimental group were subjected to palliative decompression operation,and those in control group to tumor resection operation.The clinical effectiveness,VAS,Frankel grading and ECOG were compared,and the survival rate was evaluated by Kaplan-Meier.Results 81.5% of the patients with spinal dysfunction in experimental group vs.80.0%in control group were improved in Frankel grading.Neurologic deterioration occurred in 18 patients in experimental group,and 10 patients in control group,respectively.The median time was from6 months to 13 months.Conclusion The palliative decompression operation has many advantages：shorter operating period,less intraoperative blood loss,less complications,and less surgical risks.It is a valuable therapeutic method for the elderly patients whose general situation is poor and preliminary lifetime is shorter than half a year.
出处
《骨科》
CAS
2014年第2期76-79,共4页
ORTHOPAEDICS
关键词
姑息减压手术
老年脊柱转移瘤
临床疗效
生存率分析
Palliative decompression operation
Elderly patients with spinal metastasis
Clinical effectiveness
Survival rate
