摘要
目的:观察老年慢性心力衰竭合并糖尿病的临床治疗效果分析。方法:选取本院2011年7月-2013年7月收治入院的80例老年心力衰竭合并糖尿病患者,按照随机数字表法将其分为观察组和对照组各40例,对照组给予临床常规治疗方法,观察组在常规治疗基础上给予口服卡维地洛,观察比较两组患者治疗后的治疗效果、超声心动图变化情况及血糖控制情况。结果:观察组的总有效率95.0%明显高于对照组的80.0%,差异有统计学意义(P<0.05);两组治疗后的LVEDd与LVESD均有不同程度的下降,LVEF均明显升高,而观察组的LVESD、LVEDd、LVEF均明显优于对照组,差异均有统计学意义(P<0.05);两组在治疗前血糖情况比较差异无统计学意义(P>0.05),而观察组治疗后血糖控制情况明显优于治疗前及对照组,差异均有统计学意义(P<0.05)。结论:卡维地洛在老年慢性心力衰竭合并糖尿病患者治疗中具有良好的安全性和有效性,值得临床推广应用。
Objective：To observe the clinical effect of carvedilol on elderly patients with chronic heart failure（CHF） complicated with diabetes mellitus（DM）.Method：80 elderly patients with CHF and DM were selected in our hospital from July 2011 to July 2013,they were randomly divided into the control group and the observation group,40 cases in each group. The control group was given conventional therapy,the observation group was given additional oral carvedilol on the basis of conventional therapy.The effect of treatment,the changes of ultrasound cardiogram and the control of blood glucose between the two groups were observed and compared after treatment.Result：The total effective rate of observation group was 95.0%, it was significantly higher than the control group（80.0%）,the difference was statistically significant（P〈0.05）.LVEDd and LVESD of the two groups after treatment were significantly decreased,LVEF increased significantly,while the LVESD, LVEDd and LVEF of observation group were significantly better than the control group,the differences were statistically significant（P〈0.05）.The blood sugar of two groups before treatment had no significant difference（P〉0.05）,the control of blood glucose in observation group after treatment were better than before treatment and the control group,the differences were statistically significant（P〈0.05）.Conclusion：Carvedilol may be a safe and effective drug in the treatment of elderly patients with CHF and DM,therefore,it is worthy of clinical application.
出处
《中国医学创新》
CAS
2014年第11期54-56,共3页
Medical Innovation of China
关键词
老年
慢性心力衰竭
糖尿病
卡维地洛
安全性
Elderly patients
Chronic heart failure
Diabetes mellitus
Carvedilol
Safety
