摘要
目的探讨硫辛酸联合辛伐他汀治疗急性脑梗死患者的疗效。方法随机将200例发病72 h内入院的急性脑梗死患者分为两组,分别给予血栓通注射液等常规治疗(对照组)和硫辛酸联合辛伐他汀进行治疗(治疗组)。分别于治疗后3、7、14 d对神经功能缺损程度进行评价,比较两组治疗的总有效率。结果治疗组总有效率为82%,对照组总有效率为64%,且硫辛酸联合辛伐他汀治疗后,患者神经功能明显改善,显著优于对照组(P<0.01),时间越长,疗效越好。结论硫辛酸联合辛伐他汀可作为急性脑梗死患者治疗的安全有效手段。
【Objective】To observe clinical functions of patients with cerebral infarction after the treatment of lipoic acid and Simvastatin.【Methods】200 cases of cerebral infarction occurred in 72 hours were randomly divided into control group and study group. According to the guideline, all the cases received the regular treatment,while patients in study group were combined with lipoic acid through injection. On 14th day after treatment,the executive functions were assessed with clinical nervous function deficit scale separately.【Results】The total effective rates are 64% and 82% in control group and the study group. The study group by using lipoic acid was better than the control group（P〈0.01）.【Conclusion】 lipoic acid and Simvastatin in the patients with cerebral infarction is safe and effective.
出处
《中国医学工程》
2014年第4期14-15,共2页
China Medical Engineering
关键词
硫辛酸
辛伐他汀
脑梗死
氧自由基
lipoic acid
simvastatin
cerebral infarction
oxygen free radical
