摘要
背景：结直肠癌是目前公认的可通过有效干预手段降低病死率的恶性肿瘤.目的：了解新疆地区健康体检人群的结直肠疾病患病情况,探讨对无症状人群进行结肠镜筛查的必要性.方法：纳入于2009年7月～2013年6月在新疆维吾尔自治区人民医院自愿接受结肠镜检查的无症状健康体检者,对其检查结果进行回顾性分析.结果：共1 970例体检者纳入研究,总体病变检出率为39.4％,其中结直肠息肉376例（19.1％）,结直肠癌10例（0.5％）,结肠黑变病38例（1.9％）.检出的560枚息肉中,以分布于左半结肠的管状腺瘤居多.男性息肉检出率显著高于女性（24.6％对11.2％,P＜0.001）;息肉检出率随年龄增长呈上升趋势,≥50岁年龄段人群检出率显著高于＜50岁年龄段人群（25.9％对14.3％,P＜0.05）;汉族人群息肉检出率显著高于维吾尔族和哈萨克族人群（22.6％对10.9％和10.9％,P＜0.05）.结论：本组无症状健康体检者的结直肠息肉检出率较高,患者分布具有明显的性别（男性）、年龄（≥50岁）、民族（汉族）特征.对50岁以上的无症状人群进行结肠镜筛查具有重要意义.
Background： It has been widely recognized that the mortality of colorectal cancer could be reduced by effective intervention strategies. Aims： To investigate the prevalence of co]orectal diseases in people undergoing health examination in Xinjiang Uyghur Autonomous Region and the necessity of colonoseopic screening in asymptomatic population. Methods： A retrospective analysis was carried out in asymptomatic healthy subjects who voluntarily accepted colonoscopy at Xinjiang Uyghur Autonomous Region People＇ s Hospital from July 2009 to June 2013. Results： A total of 1 970 cases were recruited in this study. The overall detection rate of colorectal lesions was 39.4%, of which 376 cases （ 19.1% ） had coloreetal polyps, 10 （0.5%） had colorectal cancer and 38 （ 1.9% ） had melanosis coll. In 560 colorectal polyps detected, tubular adenoma located at left hemieolon was more frequent than other types of polyps. The prevalence of eolorectal polyps was higher in males than in females （24.6% vs. 11.2% , P 〈0.001 ） and increased with the advancing of age （ ≥50 years old vs. 〈50 years old： 25.9% vs. 14.3%, P 〈 0.05 ）. More polyps were detected in Han nationality than in Uyghur and Kazak （22.6% vs. 10.9% and 10.9%, P 〈0.05）. Conclusions： The prevalence of colorectal polyps is fairly high in asymptomatic healthy subjects. Males and individuals with advancing age （ ≥50 years old） and Han nationality are more prone to have colorectal polyps. For asymptomatic subjects above 50 years old, screening for colorectal diseases by eolonoscopy is worthwhile.
出处
《胃肠病学》
2014年第4期221-224,共4页
Chinese Journal of Gastroenterology
关键词
健康体检
结肠镜检查
筛查
息肉
结直肠肿瘤
Health Examination
Colonoscopy
Screening
Polyps
Colorectal Neoplasms
