摘要
目的探讨乳腺癌保乳手术的疗效及其生存质量。方法选取180例早期乳腺癌患者,其中56例患者行保乳手术,63例患者行标准根治手术,61例患者行改良根治术。结果保乳手术组具有住院时间较少、手术时间较短、术中出血少等优势,与根治术组(标准根治术组+改良根治术组)相比,差异有统计学意义(P<0.05)。3组患者的生存率、远处转移率、术后复发率差异无统计学意义(P>0.05),保乳手术组患者的心理因子、躯体因子、精神因子和社会支持因子4个方面均显著高于标准根治术组和改良根治术组患者(P<0.05);保乳手术组、标准根治术组及改良根治术组患者术后乳房外观及美容效果差异有统计学意义(P<0.05)。结果早期乳腺癌患者保乳手术的近期疗效较满意,严格掌握相关手术指征、规范切除和术后放化疗等综合治疗措施是保乳手术成功的关键。
Objective To analyze the quality of life and curative effect in breast cancer patients. Methods The clinicopathologic data of elder women with breast cancer who undergone breast-conserving therapy （56 cases）, standard radical mastectomy （63 cases） and modified radical mastectomy （61 cases） in our hospital were retrospectively analyzed. Results We found that hospitalization time, operative time, blood loss decreased signi？ cantly in breast-conserving surgery group compared with radical surgery group （ standard radical surgery group ＋ modified radical mastectomy group ） （ P 〈 0. 05 ） ; No significant differences were identified among all groups in survival, distant metastasis, recurrence rate. （ P 〉 0. 05 ） ; psychological factors, physical factors, mental factors and social support factors in breast-conserving surgery group were significantly higher than those in radical surgery group （ P 〈 0. 05 ） ; Compared with radical surgery groups, breast appearance and cosmetic results had significant differences in breast-conserving surgery group （ P 〈 0. 05 ）. Conclusion For early stage breast cancer patients, breast-conservative surgery including tumorectomy and auxiliary dissection followed by post-operative adjuvant chemotherapy and radiotherapy lead to excellent local control. Appropriate operative methods lead to good cosmetic results.
出处
《中国肿瘤临床与康复》
2014年第5期525-527,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
乳腺肿瘤
保乳手术
放化疗
老年人
Breast neoplasms
Breast-conserving surgery
Chemotherapy
Elder patients
