摘要
目的探讨颈动脉狭窄（carotidarterystenosis，CAS）患者的焦虑和抑郁状态，以及脑缺血症状和脑梗死灶对焦虑和抑郁状态的影响。方法使用WilliamWK．Zung编制的焦虑自评量表（Self-RatingAnxietyScale，SAS）和抑郁自评量表（Self-RatingDepressionScale，SDS），对93例在北京协和医院血管外科住院治疗的颈动脉狭窄患者的焦虑和抑郁状态严重程度进行评价，并以同时期住院的146例下肢静脉曲张患者作为对照组。结果颈动脉狭窄患者SAS、SDS评分显著高于静脉曲张组[SAS：（32＋8）分和（29±7）分，P〈0．001；SDS：（42±14）分和（35±11）分，P〈0．001]。此外，颈动脉狭窄症状组与非症状组[SAS：（32±8）分和（32±7）分，P=0．780；SDS：（41＋14）分和（42±14）分，P=0．830]、脑梗死灶组与非脑梗死灶组[SAS：（31±8）分和（33±8）分，P=0．147；SDS：（39±14）分和（43±13）分，P=0．241]，SAS、SDS评分结果差异无统计学意义。结论颈动脉狭窄患者较易发生焦虑和抑郁等情感障碍，且与颈动脉狭窄患者是否伴发近期脑缺血症状和有无脑梗死灶无关。
Objective To investigate the distribution of anxiety and depression disorders in patients of carotid artery stenosis （ CAS ） , and the relationship between symptoms of cerebral infarction and the severity of anxiety and depression. Methods We used Self-Rating Anxiety Scale （SAS） and Self-Rating Depression Scale（SDS） created by William W. K. Zung to evaluate the anxiety and depression disorders associated with CAS in 93 patients hospitalized at the Department of Vascular Surgery, and 146 hospitalized varicose veins patients as acontrols. Results The scales of CAS are significantly higher than the control group（ SAS ： 32 ± 8 vs 29 ± 7, P 〈 0. 001 ; SDS.42 ± 14 vs 35 ±11, P 〈 0. 001 ）, within-group analysis of CAS shows that there is no statistical difference between symptomatic group and non-symptomatic group （SAS.32±8 vs 32 ±7,P =-0. 780;SDS：41 ± 14 vs 42±14,P =0. 830） ,or between infarction group and non-infaetion group （ SAS： 31 ±8 vs 33 ± 8, P = 0. 147; SDS： 39 ± 14 vs 43± 13, P = 0.241 ）. Conclusiorts CAS can cause anxiety and depression disorders, and the disorders are not related to symptoms of cerebral ischemia and cerebral infarction.
出处
《中华普通外科杂志》
CSCD
北大核心
2014年第5期385-387,共3页
Chinese Journal of General Surgery
基金
中央保健专项基金老年颈动脉狭窄手术安全预警和优化策略基金资助项目（N20098080）
关键词
颈动脉狭窄
焦虑
抑郁
Carotid stenosis
Anxiety
Depression
