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沙丁胺醇雾化吸入治疗老年型哮喘发作的临床疗效 被引量:4

Curative effect of albuterol aerosol inhalation in the treatment of elderly asthmatic
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摘要 目的:研究探讨沙丁胺醇雾化后经吸入给药法治疗老年型哮喘发作的临床疗效和应用价值。方法选取2011年2月~2012年2月在本院接受治疗86例老年哮喘患者。随机分成对照组和观察组,每组43例。对照组采用常规的祛痰、平喘、吸氧和抗感染治疗,观察组在对照组的基础上再给予雾化沙丁胺醇吸入法进行治疗,治疗前后均要测定两组患者的的PaCO2、PaO2和FEV1,并观察记录患者的咳、喘、痰症状,听诊肺部哮喘音。结果两组患者经治疗后均有显著疗效,但观察组的总有效率为93.0%明显高于对照组的81.4%,并且肺功能和血气分析均明显改善,差异具有统计学意义(P〈0.05)。结论联用沙丁胺醇雾化吸入治疗老年型哮喘的疗效更显著,应用价值更高,值得广泛推广治疗老年型哮喘发作。 Objective To discuss and explore the clinical efficacy and application value of albuterol aerosol inhalation in the treatment of elderly asthmatic. Methods There were 86 cases of elderly patients with asthma in our hospital from February 2011 to February 2012 and randomly divided them into treatment group and control group, 43 cases for each group. The patients in the control group were given conventional therapy of making expectoration easy, relieving asthma, oxygen uptake and anti-infection;the patients in the treatment group were given albuterol aerosol inhalation on the basis of the control group therapy. Measure the PaCO2, PaO2 and FEV1 of the patients in both groups before and after treatment, at the same time, observe and record the symptoms of the coughing, gasping and expectoration. In addition, auscultate the wheezing rale from the lungs. Results Both of the 2 groups were of significantly efficacy, but the total efficiency of the treatment group(93.0%) was significantly higher than the control group(81.4%). Furthermore, both lung function and blood gas analysis improved significantly and the difference between the treatment group and control group was statistically significant (P〈0.05). Conclusion The combination therapy of the albuterol aerosol inhalation in the treatment of elderly asthmatic has significant efficacy and higher application value, which is worth of clinical promotion.
出处 《中国现代药物应用》 2014年第10期13-14,共2页 Chinese Journal of Modern Drug Application
关键词 沙丁胺醇 雾化吸入 老年型哮喘 临床疗效 Albuterol Aerosol inhalation Elderly asthmatic Clinical effect
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