摘要
目的 探讨全程护理管理模式在AIDS免费治疗门诊中的应用效果.方法 将72例HIV感染者/AIDS患者按照随机数字表法,遵循自愿参加的原则分为干预组34例和对照组38例,对照组采用常规护理管理模式,干预组采用全程护理管理模式,干预1年后观察并分析两组患者7项依从性指标.结果 干预组从HIV确认到首次CD4细胞检测的间隔时间为20d,首次发现CD4细胞≤350个/μl到抗病毒治疗的时间间隔为30 d,分别低于对照组的30,60d,差异有统计学意义（Z分别为3.42,3.13;P＜0.01）;服药完全依从、部分依从构成比分别为82.4％,14.7％,优于对照组（52.6％,34.2％）,差异具有统计学意义（Z=-2.693,P＜0.01）;规范随访构成比为82.4％,优于对照组55.3％,差异具有统计学意义（x2 =6.057,P＜0.05）;每3个月接受CD4细胞检测的比例97.1％,抗病毒治疗6～12个月CD4细胞增长≥100个/μl的比例为79.4％,治疗6～12个月病毒抑制的比例为82.4％,明显优于对照组（81.6％,44.7％,60.5％）,差异有统计学意义（x2分别为4.354,5.678,4.138;P ＜0.05）.结论 全程护理管理模式能督促AIDS患者CD4细胞检测及规范随访,促进尽早治疗,提升患者服药依从性,提高治疗效果,降低AIDS相关疾病发生率和死亡率.
Objective To explore the application effect of throughout nursing management mode in the free treatment of acquired immune deficiency syndrome （AIDS） in outpatient.Methods Follow the principle of voluntary participation,seventy-two infected person or patients with AIDS were chosen and were divided into the intervention group （n =34） and the control group （n =38）.The control group received the routine nursing management mode,and the intervention group received the throughout nursing management mode.The seven compliance indicators were observed and analyzed one year after the intervention.Results The average interval time from confirming HIV to detecting CD4 cell count firstly was 20 d,and the average interval time from finding CD4 less than 350/μl firstly to antivirus treatment was 30 d in the intervention group,and were lower than 30 d,60 d in the control group,and the differences were statistically significant （Z =3.42,3.13,respectively; P 〈 0.01）.The proportions of full compliance,partial compliance in the intervention group were respectively 82.4%,14.7%,and were better than those in the control group（52.6%,34.2%）,and the difference was statistically significant （Z =-2.693,P 〈 0.01）.The proportions of the standard of follow-up in the intervention group were respectively 82.4%,and were better than 55.3% in the control group,and the difference was statistically significant （x2 =6.057,P 〈 0.05）.The proportions of detecting CD4 cell count every three months,the increased CD4 more than 100/μl 6-12 months after the antivirus treatment,the viral suppression 6-12 months after the treatment in the intervention group were respectively 97.1%,79.4%,82.4%,and were better than 81.6%,44.7%,60.5% in the control group,and the differences were statistically significant （x2 =4.354,5.678,4.138,respectively; P 〈 0.05）.Conclusions The throughout nursing management mode can urge the patients to detect CD4 cell count and standardize the follow-up,and can promote the patients to treat as soon as possible,and increase the medication compliance,and improve the treatment effect,and reduce the incidence and mortality of AIDS-related diseases.
出处
《中华现代护理杂志》
2014年第13期1529-1532,共4页
Chinese Journal of Modern Nursing
基金
广西科技攻关项目（桂科攻1140003B-62）
广西卫生厅中医药科技专项（GZPT1224）
广西卫生厅重点科研课题（重2011038）
关键词
获得性免疫缺陷综合征
全程护理管理
服药依从性
治疗
随访
Acquired immune deficiency syndrome
Throughout nursing management
Medication compliance
Treatment
Follow-up
