摘要
目的评价透明质酸敷料对超脉冲CO2点阵激光术后的修复作用和安全性。方法轻至重度痤疮后凹陷性瘢痕,并接受超脉冲CO2点阵激光治疗的患者82例,分为试验组和对照组,每组41例。试验组:激光治疗后外敷透明质酸敷料20 min,共10 d;对照组:不用敷料,其余处理同试验组。观察治疗后红斑、水肿、灼热等急性炎症反应情况,第10天复诊观察结痂情况,进行患者舒适度评价,第30天复诊观察色素沉着发生情况。结果试验组急性炎症反应评分优于对照组(P<0.01),全部痂皮脱落时间试验组短于对照组(P<0.05),患者激光术后自身主观感受和舒适程度评价试验组优于对照组(P<0.05),试验组炎症后色素沉着发生率低于对照组(P<0.05)。结论透明质酸敷料用于点阵激光术后可减少术后不良反应发生率,提高患者满意度。
Objective To evaluate the effectiveness and safety of hyaluronic acid dressings applied after ultra-pulse carbon-dioxide fractional laser therapy. Methods Altogether 82 post-aene patients with facial atrophy scar were enrolled in this study. After the treatment with ultra-pulse carbon-dioxide fractional laser, the patients were randomly divided into two groups. The patients in the experiment group were smeared with hyaluronic acid dressings on the face for20 minutes immediately after the laser therapy, and then once per day for 10 days. Except hyaluronic acid dressings, the patients in the control group were treated just as those in the experiment group. Inflammatory reactionswere measured semi-quantitatively, such as erythema, edema and burning sensation. The time for crust formulation/desquamation and comfort level of patients was evaluated on day 10. The post-inflammatory hyperpigmentation rate was compared on day 30. Results Compared with the control group, the experimental group showed a better improvement of acute inflammatory responses （P 〈 0. 01 ）. The period of complete desquamation of crusts were significantly different（P 〈 0. 05） between the two groups. Statistical difference （P 〈 0. 05） was observed in comfort level of patients between them. The incidence rate of PIH was lower （P 〈 0. 05） in the experiment group than in the control group. No adverse reaction was reported in the triM. Conclusions Hyaluronic acid dressings are effective inreducing side-effects after fraction carbon-dioxide laser and improving patients satisfaction.
出处
《中国激光医学杂志》
CAS
CSCD
2014年第2期90-93,114,共5页
Chinese Journal of Laser Medicine & Surgery
关键词
激光
透明质酸
痤疮瘢痕
Hyaluronic acid
Fraction carbon-dioxide laser
Ache scar
