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新辅助化疗TAC与TP方案治疗三阴性乳腺癌的疗效和安全性

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摘要 目的探讨新辅助化疗TAC与TP方案治疗三阴性乳腺癌的疗效和安全性。方法选取我院收治的98例三阴性乳腺癌患者,随机将其分为观察组和对照组,各49例,观察组行TAC化疗,对照组行TP化疗,对两组患者的近期疗效及不良反应进行对比。结果两组患者病理完全缓解率及治疗总有效率比较无显著性差异(P〉0.05);观察组患者的肿瘤进展率明显低于对照组郁程度明显低于常规(P〈0.05),观察组3例患者出现房性前期收缩,对照组中4例患者出现2级肾功能损伤;观察组患者的3~4级脱发率及学毒性明显高于对照组,观察组患者的3-4级胃肠道反应明显低于对照组。结论新辅助化疗TAC与TP方案对治疗三阴性乳腺癌均能取得良好的效果,且不良反应患者均可耐受。
出处 《中国医药指南》 2014年第15期209-210,共2页 Guide of China Medicine
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