摘要
目的对纯钛表面进行抗菌改性,以降低纯钛种植体周围炎的发生率,从而提高种植术的成功率。方法采用水相硅烷化方法,将3-(氨基丙基)三乙氧基硅烷(APS)组装在湿化学法处理的钛表面上,并将纳米银被覆在该表面上,采用X射线光电子能谱(XPS)和X射线能谱(EDX)对该改性表面理化性能进行分析,观察其对金黄色葡萄球菌和大肠杆菌的抗菌性能。结果扫描电镜观察可见,改性后的钛表面有不规则纳米银颗粒散在的附着在其表面上,XPS分析显示银的含量为6.8%。经过24 h需氧培养,纳米银改性钛片对金黄色葡萄球菌的抗菌率达到94.23%,对大肠杆菌的抗菌率达95.34%。结论经过纳米银改性后的钛片具有抗菌性能。
Objective To deposit silver nanoparticles on a titanium surface to obtain antibacterial properties. To reduce the incidence of peri-implantitis, and improve the success rate of implantation. Methods A silver nanoparticle-modified titanium （Ti-nAg） surface was prepared using silanization method, and its surface was characterized by using X-ray photoelec-tron spectroscopy （XPS） and energy dispersive X-ray spectrometer （EDX）. Two species of bacteria, namely, Staphylococcus aureus and Escherichia coli, were used to test the antibacterial effect of Ti-nAg surface. Results Scanning electron micro-scope （SEM） revealed that a small quantity of silver nanoparticles were deposited on the titanium surface. XPS analyses revealed that 6.8% of silver was present on the titanium surface. After 24 h of incubation, 94.23% of Staphylococcus aureus and 95.34% of Escherichia coli were killed on the Ti-nAg surface. Conclusion Results suggest that silver nanoparticle-modified titanium is a promising material with an antibacterial property that may be used as an implantable biomaterial.
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
2014年第3期303-305,共3页
West China Journal of Stomatology
关键词
钛
纳米银
抗菌性能
水相硅烷化
titanium
nano-silver
antibacterial activity
silanization method
