摘要
分开抚养双生子研究设计思路巧妙，被喻为“大自然的迷人实验（fascinating experiment of nature）”，是不可多得的遗传流行病学资源。但是限于研究样本获取的艰难性，开展数量有限，这也使得目前仅存的分开抚养双生子研究显得尤为珍贵。如何更为充分地利用这些资源将是这一研究方向所关注的重点。本文将对分开抚养双生子研究产生的背景、基本设计思路、目前国外经典的分开抚养双生子研究实例以及对于国内该领域研究的启示进行介绍。
The design of twins reared apart, very rare genetic epidemiological resources has been hailed as ＂fascinating experiment of nature＂. However, not so many studies have been based on it due to the difficulty in recruiting the participants. It also makes the only existing research on twins raised apart particularly valuable. How to utilize these resources fully will be the focus of this research area. This review will overview its design background, basic hypothesis, and current status of research and give advice for the research in this field in China.
出处
《中华医学遗传学杂志》
CAS
CSCD
北大核心
2014年第3期327-329,共3页
Chinese Journal of Medical Genetics
基金
国家自然科学基金（81202264）
卫生行业科研专项（201002007）
关键词
双生子研究
遗传
环境
儿童抚养
Twin study
Genetic variation
Environment
Child rearing
