摘要
目的:探讨对维持性血液透析(MHD)患者应用阿司匹林降低心脑血管事件的疗效和安全性。方法:选取100例透析充分的MHD患者为研究对象,随机分为治疗组和对照组,每组50例,治疗组患者给予阿司匹林治疗。结果:与对照组比较,治疗组心脑血管事件发生率明显降低(P<0.05),出血事件无显著差异(P>0.05)。透析时间、血磷、spKt/V是MHD患者发生心脑血管事件的独立影响因素。结论:阿司匹林可有效降低MHD患者心脑血管事件发生,且危险性无显著增加。
Objective： To observe the efficacy of reducing cardiovascular events and safety in maintenance hemodialysis （ MHD） patients taked aspirin .Methods：100 cases of MHD patients with dialysis adequacy were randomly divided into treatment group and control group , 50 cases in treatment group were treated with aspirin . Results：The incidence of cardiovascular and cerebrovascular events in treatment group was significantly lower than control group（P〈0.05）.No significant difference was found in bleeding events between the two groups （ P 〉0.05）.Duration of dialysis, phosphorus, spKt/V were independent factors of cardiovascular and cerebrovascular events in hemodialysis patients .Conclusion： Aspirin can reduce cardiovascular and cerebrovascular events in MHD patients , and have no significant increase in risk .
出处
《东南大学学报（医学版）》
CAS
2014年第3期327-331,共5页
Journal of Southeast University(Medical Science Edition)
基金
上海市科委科研基金资助项目(124119b1100)
关键词
阿司匹林
维持性血液透析
心脑血管事件
aspirin
maintenance hemodialysis
cardiovascular and cerebrovascular events
