摘要
目的通过两种方法检测血清肌钙蛋白I结果的比较,探讨Nano checker 710的临床应用价值。方法收集340例患者血清在Abbott i4 000和Nano checker 710上同时检测cTnI含量。对检测结果进行回归分析,以Abbott i4 000结果为标准比较两种方法阳性检出率并绘制ROC曲线。结果 i4 000和Nano checker710检测总阳性率分别为91.18%、66.18%,两者间差异有统计学意义;低浓度组两种方法检出率差异有统计学意义,但阴性组和高浓度组差异无统计学意义;低浓度组、高浓度组两种方法的相关系数分别为0.350、0.749。checker 710的ROC曲线下面积为0.903。结论 Nano checker 710检测血清cTnI特异性高,但敏感性稍低,适用于急性心血管病患者的急诊检测和初步筛查,但对于溶血的标本和与临床不符合的标本需要在i4 000进行检测。
Objective To compare the two methods by the results of serum troponin I, and explore the clinical value of Nano checker 710. Methods 340 cases of patients with simultaneous detection of serum cTnI levels in the Abbott i4000 and Nano checker 710. Regression analysis of test results to the results of a standard Abbott i4000 positive rate comparison of two methods and draw the ROC curve. The results i4000 and Nano checker 710 total positive rates were 91.18%, 66.18%, the difference was statistically significant; low concentration detection rate between the two methods was statistically significant, but the negative group and the high concentration of group differences No statistically significant; correlation coefficient low concentration, high concentration of the two methods were 0.350,0.749. the area under the ROC curve was 0.903 checker 710. Conclusion Nano checker 710 serum cTnI high specificity, but lower sensitivity for acute cardiovascular disease detection and emergency preliminary screening, but for hemolysis and clinical specimens and specimens do not meet the need for testing or i4000 confirmation.
出处
《襄阳职业技术学院学报》
2014年第3期38-40,43,共4页
Journal of Xiangyang Polytechnic
关键词
心肌肌钙蛋白I
化学发光法
免疫层析定量法
cardiac troponin I
chemiluminescence
Immunochromatography quantitative method
