摘要
目的比较等效剂量地佐辛与芬太尼用于腹腔镜下阑尾炎术后镇痛对患者血流动力学的影响。方法选择择期行腹腔镜下阑尾炎手术的患者60例,年龄20~60岁,随机分为A组（地佐辛组）和B组（芬太尼组）,每组30例。两组患者术后第1次感到疼痛时分别静注地佐辛0.15 mg/kg或芬太尼1.5μg/kg。记录用药前及用药后5、10、30 min的血压、心率、SpO2;记录用药前及用药后1、2、4、8 h的VAS评分及不良反应发生情况。结果两组患者用药前血压、心率无明显差异;用药后10、30 min A组收缩压、舒张压及心率均明显低于B组;两组术后镇痛期间各时点疼痛VAS评分差异无统计学意义;两组术后不良反应发生情况,A组明显低于B组,以恶心呕吐、头痛为主。结论地佐辛因其良好的镇痛效果、稳定机体血流动力学、用药后不良反应发生少,能够广泛用于腹腔镜下阑尾炎患者的术后镇痛。
Objective To study the effects of dezocine or fentanyl on hemodynamics for postoperative analgesia in laparoscopic appendectomy. Methods Sixty patients,age from 20 to 60,scheduled for selective laparoscopic appendectomy under general anesthesia were randomly divided into two groups with 30 cases each. Group A and B received intravenous injection of dezocine 0. 15mg /kg and fentanyl 1. 5 μg /kg when the first time felt pain after surgery,respectively. Record BP,HR and SpO2before and 5,10,30 min after injection; Record Vas score and complications before and 1h,2h,4h,8h after injection. Results There is no significant difference between group A and B in BP,HR before injection. At 10min,30min after injection,SBP,DBP and HR of group A is significantly lower than group B. There is no significant difference between group A and B in VAS scores. Complications of group A is lower than group B,especially in headache,nausea and vomiting. Conclusion Due to it effects on analgesia,stabilizing hemodynamics and reduction of complications,dezocine can be widely used in postoperative analgesia of laparoscopic appendectomy.
出处
《现代医院》
2014年第5期45-47,共3页
Modern Hospitals
