摘要
目的探讨高危非肌层浸润性膀胱癌是否有必要行二次经尿道膀胱肿瘤电切术。方法将高危非肌层浸润性膀胱癌60例患者随机分成两组:研究组为二次电切组30例,对照组为非二次电切组30例。术后膀胱镜检查随访2年,比较两组肿瘤2年复发率、进展率、并发症发生率、住院费用及住院天数。结果研究组和对照组2年肿瘤复发率和疾病进展率分别为13.3%和26.6%、10.0%和16.6%,组间比较差异均无统计学意义(P>0.05)。围手术期研究组与对照组发生并发症分别为8例和2例,组间比较差异有统计学意义(P<0.05)。研究组医疗费用(平均1.5万元)低于对照组(平均1.0万元)。住院时间研究组平均7天,对照组平均13天,二者差异有统计学意义(P<0.05)。结论二次电切在降低高危非肌层浸润性膀胱癌的复发及进展方面并不优于非二次电切,对高危非肌层浸润性膀胱癌行常规二次电切是没有必要的。
Objective To explore the necessity of second transurethral resection of bladder tumor （TURBT） for treating high-risk non-muscle-invasive bladder cancer .Methods 60 cases of high-risk non-muscle-invasive bladder cancer were randomly divided into two groups .The 30 cases in the research group received second transurethral resection ,w hile the 30 cases in the control group did not .Postoperative cys-toscopy was conducted in the 2-year follow-up surveys .The recurrence of tumor ,the progress rates ,the recurrence of complication ,the hospitalization expenses and the hospital stay of the two groups were com-pared .Results The recurrence of tumor was 13 .3% in the research group and 26 .6% in the control group （ P 〉0 .05） .The progress rate was 10/0% in the research group and 16 .6% in the control group（ P〉0 . 05） .Complications occurred in 8 cases in the research group and 2 cases in the control group （ P〈0 .05） . The average medical expense was RMB 15 ,000 in the research group and RMB 10 ,000 in the control group .The average hospital stay was 7 days in the research group and 13 days in the control group （ P 〈0 .05） .Conclusion Second TURBT for treating high-risk non-muscle-invasive bladder cancer is no superior to non-second TURBT .It is not necessary to perform second TURBT for treating high-risk non-muscle-invasive bladder cancer .
出处
《山东医学高等专科学校学报》
2014年第2期81-84,共4页
Journal of Shandong Medical College
基金
临沂市2012年科技发展计划项目(No:201213059)
