摘要
目的：分析接受手术治疗的成人急性阑尾炎预后和抗生素选用之间的关系。方法：回顾分析2011至2012年间,我院接受手术治疗的93例急性阑尾炎患者。定义急性单纯性阑尾炎和化脓性阑尾炎为轻型阑尾炎,坏疽性阑尾炎和穿孔性阑尾炎为重型阑尾炎。选取住院天数和重型阑尾炎的发生率为预后判断指标,分析抗生素选用和预后之间的关系。结果：全部患者接受了抗生素治疗,其中氟喹诺酮类有45例（占48.4%）,头孢类41例（占44.1%）,碳青霉烯类7例（占7.5%）。93例患者中有25例为重型阑尾炎,抗生素的选用种类和重型阑尾炎的发生之间差异无统计学意义（P〉0.05）。住院天数为1~34d,平均（5.7±5.1）d,选用氟喹诺酮的患者住院天数比选用头孢者平均短2.6d（P〈0.01）。结论：对急性阑尾炎患者而言,选用何种抗生素并不会减少重型阑尾炎的发生,但选用氟喹诺酮类抗生素有可能比选用头孢类能减少住院天数。
Objective：To investigate the association between antibiotic selection and outcomes of adult acute appendicitis who underwent appendicectomy.Method：A retrospective analysis of all 93patients who underwent appendicectomy from 2011to 2012was made.We defined simple appendicitis and suppurative appendicitis as mild appendicitis.The gangrenous appendicitis and perforating appendicitis were defined as advanced appendicitis.The occurrence of advanced appendicitis and length of stay were the two major items for us to analysis the association between antibiotics and the outcomes of acute appendicitis.Result：All patients received antibiotics therapy.45patients received quinolones（48.4%）,41patients received cephalosporins（44.1%）,the 7left patients were given carbapenems（7.5%）.25advanced appendicitis were explored.There is no statistic difference between antibiotic selection and the occurrence of advanced appendicitis（P=0.3337）.The length of stay varied from 1day to 34days on average of（5.7±5.1）days.The average stay of the patients receiving quinolones is 2.6days shorter than patients who were given cephalosporins（P=0.0085）.Conclusion：The antibiotics selection has no relationship with the occurrence of advanced appendicitis.The hospital stay time may be reduced when selecting quinolones compared with cephalosporins.
出处
《临床急诊杂志》
CAS
2014年第5期245-248,共4页
Journal of Clinical Emergency
关键词
阑尾炎
抗生素
appendicitis
antibiotics
