摘要
目的评价后腹腔镜泌尿外科手术致腹膜腔感染的抗菌药物应用效果,以期为提高临床采用腹腔镜泌尿外科手术治疗患者的水平提供参考。方法对医院2011年1月-2013年3月行后腹腔镜泌尿外科手术患者的手术资料进行回顾性分析,随机将手术患者分为对照组(230例)与观察组(270例),比较两组患者抗菌药物使用差异。结果对照组手术患者预防用药率为100.00%,而观察组手术患者预防用药率为81.85%,显著低于对照组,差异有统计学意义(P<0.05);观察组的单一用药率为77.41%,显著高于对照组的68.26%,联合用药率为4.44%,显著低于对照组的31.74%,差异均有统计学意义(P<0.05);观察组患者术前、术后抗菌药物使用合理率显著高于对照组,差异有统计学意义(P<0.05)。结论为预防后腹腔镜泌尿外科手术后引起后腹膜腔感染,必须合理使用抗菌药物,同时避免广谱抗菌药物造成细菌耐药现象的出现。
OBJECTIVE To evaluate the effect of antimicrobial agents on peritoneal cavity infections after retroperitoneoscopic operation, in order to provide basis for improving the level of treatment of patients with retroperitoneoscopic operation. METHODS The surgery data of patients with retroperitoneoscopic operation from Jan 2011 to Mar 2013 were retrospectively analyzed and divided into control group （230 cases） and medication group （270 cases） according to use of antibiotics or not, and the difference of the use of antibiotics in the two groups was compared. RESULTS In the control group, preventive medication rate was 100~, the treatment group 81.85%, which was significantly lower than the control group （P^0.05）. The single drug treatment rate of medication group was 77.41%, significantly higher than the control group 68.26%, while combination therapy rate of medication group was 4.44%, significantly lower than the control group 31.74% （P〈0.05）. The rational utilization rate of antibiotics of medication group was significantly higher than control group before and after operation （P〈0.05）. CONCLUSION Antimicrobial agents should be used reasonably, in order to prevent from retroperitoneal infection after retroperitoneoscopic operation and avoid the occurrence of bacterial resistance phenomenon induced by broad-spectrum antibiotics.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第11期2771-2772,2775,共3页
Chinese Journal of Nosocomiology
基金
无锡市卫生局重点扶持计划基金资助项目(WW-2010B-031)
关键词
后腹腔镜
泌尿外科
感染
抗菌药物
Retroperitoneoscopic
Urology
Infection
Antimicrobial drug
