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胰岛α细胞胰岛素抵抗和2型糖尿病 被引量:4

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摘要 一般认为胰岛素抵抗和胰岛细胞功能障碍是2型糖尿病发生的两个主要病理生理学机制,而胰高血糖素的作用很少提及。传统胰岛素抵抗(IR)的定义是指胰岛素的外周靶器官或靶组织(主要是肝脏、脂肪组织和骨骼肌)对胰岛素的敏感性降低,导致正常量的胰岛素生物学效应低于正常水平。
作者 谢敏 李竞
出处 《临床内科杂志》 CAS 2014年第5期354-355,共2页 Journal of Clinical Internal Medicine
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