摘要
目的探讨肿瘤患者发生医院感染的相关因素及预防对策,为降低医院感染发生提供依据。方法回顾性分析2010年2月-2013年2月收治的1 837例恶性肿瘤患者临床资料,医院感染诊断参照《医院感染诊断标准》,调查数据应用SPSS13.0软件进行统计分析。结果 1 837例恶性肿瘤患者发生医院感染92例,感染率为5.01%,感染部位以呼吸系统为主,占50.00%;92例发生医院感染患者中肺癌患者感染占38.04%,肿瘤分期以IV期患者感染为主,占59.78%;共检出病原菌92株,其中革兰阴性菌49株占53.26%,革兰阳性菌30株占32.61%,真菌13株占14.13%;感染与非感染患者的年龄、营养状况、抗菌药物应用、住院天数、放化疗次数和侵入性操作等因素比较,差异有统计学意义(P<0.01)。结论肿瘤患者治疗期间身体虚弱,免疫能力低下,易受病原菌侵袭而发生医院感染,针对易感因素采用相应的预防对策,可有效降低医院感染率。
OBJECTIVE To explore the related factors causing nosocomial infections to tumor patients and the countermeasures so as to provide evidence for reducing the nosocomial infections .METHODS The clinical data of 1837 cases of patients with malignant tumor treated in the hospital from Feb 2010 to Feb 2013 were retrospectively analyzed;the nosocomial infection was diagnosed as per ＂Nosocomial Infection Diagnosis Criteria＂ and the data were statistically analyzed with SPSS 13 .0 software .RESULTS Totally ,92 of the 1837 cases patients with malignant tumor suffered nosocomial infections ,with the infection rate of 5 .01% .Respiratory system dominated the infection sites ,accounting for 50 .00% ;of the 92 patients who suffered nosocomial infections ,lung cancer patients accounted for 38 .04% ;patients at Ⅳ stage dominated the infected patients of different stages ,accounting for 59 .78% ;a total of 92 pathogens were detected ,including 49 （53 .26% ）strains of gram-negative bacteria ,30 （32 .61% ）strains of gram-positive bacteria strains and 13 （14 .43% ） strains of fungi;there was significant difference between the infected patients and uninfected patients′ age ,nutritional status ,antibiotic use ,hospital stays ,reception times of chemotherapy and invasive operations and other factors in patients with and without infections ,the difference was significant （P〈0 .01） .CONCLUSIONS Tumor patients are in poor health during treatment with poor immunity , and are susceptible to suffer nosocomial infections for pathogen invasion , therefore ,it is required to take corresponding countermeasures for susceptible factors and effectively reduce the nosocomial infection rate .
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第12期2982-2984,共3页
Chinese Journal of Nosocomiology
基金
浙江省科技厅公益性技术应用研究计划基金资助项目(2012C33022)
关键词
恶性肿瘤
医院感染
相关因素
预防对策
Malignant tumor
Nosocomial infection
Related factor
Countermeasures
