摘要
目的:评价腺苷钴胺针剂治疗单纯性老年瘙痒症的疗效。方法:将80例患者随机分为两组,治疗组40例,给予腺苷钴胺针剂1.0 mg肌注,每日1次;外用尿素软膏,每日2次。对照组40例,单独给予尿素软膏外用,每日2次。治疗2周后评价疗效和不良反应。结果:治疗组和对照组的总有效率分别为62.5%和27.5%,差异有显著性(P<0.01)。两组治疗过程中均未出现不良反应。结论:腺苷钴胺针剂治疗单纯性老年瘙痒症安全、有效。
Objective：To assess the therapeutic efficacy of adenosylcobalamin injection in the treatment of simple senile pruritus. Methods：Eighty patients were divided randomly into two groups. The treatment group （40 cases） was treated with adenosylcobalamin injection （1.0 mg, intramuscularly）, once a day, and topical urea ointment, twice daily. The control group （ 40 cases） was treated with topical urea ointment only, twice daily. The therapeutic effects and the adverse effects were assessed at week 2 after the treatment. Results：The total clinical efficacies in the treatment group and control group was 62. 5% and 27. 5% respectively, with a statistically significant difference （P〈0.01）. There were no adverse effects in the two groups. Conclusion：Adenosylcobalamin injection is safe and effective in treatment of senile pruritus.
出处
《中国麻风皮肤病杂志》
2014年第5期296-297,共2页
China Journal of Leprosy and Skin Diseases
关键词
腺苷钴胺针
老年瘙痒症
denosylcobalamin injection
senile pruritus
