摘要
目的:研究复方利多卡因乳膏联合卤米松乳膏治疗瘙痒性皮肤病的临床疗效。方法:将92例经临床诊断为慢性湿疹、神经性皮炎、结节性痒疹的患者随机分为治疗组和对照组,治疗组采用复方利多卡因乳膏和卤米松乳膏联合治疗,对照组单用卤米松乳膏治疗,一天两次患处涂抹,共治疗14 d。结果:治疗一周后治疗组疗效积分明显低于对照组,差异有统计学意义(P<0.05),治疗2周后2组差异具有极显著统计学意义(P<0.01)。治疗组和对照组总有效率分别为93.3%和75.6%,差异有统计学意义(P<0.05),表明治疗组疗效显著优于对照组。结论:复方利多卡因乳膏与卤米松乳膏合用后,无论是患者瘙痒症状的缓解速度还是最终治疗效果上,都明显优于单纯使用卤米松。
OBJECTIVE To investigate the clinical effects of combined usage of compound lidocaine cream and halometasone cream on the treatment of pruritic skin disorder. METHODS A total of 92 patients who were diagnosed with eczema, neuro- dermatitis and prnrigo nodularis were randomly divided into therapy group and control group. The patients in therapy group were treated with combined usage of compound lidocaine cream and halometasone cream while those in control group were re- ceived only application of halometasone cream twice a day for 14 days. RESULTS Significant differences of integrals of symp- toms and signs were found between therapy group and control group after one week＇s treatment （P〈0. 05） and after two weeks＇ treatment （P〈0. 01）. The total effective rates were 93.3% and 75.6%, with significant difference between them （P〈0. 05）, in therapy group and control group respectively, indicating a better effect in therapy group than in control group. CONCLUSION Both the improving speed of itch and finally clinical effects were better by the combined usage of compound li- docaine cream and halometasone cream than by the treatment of halometasone cream alone.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2014年第11期918-920,共3页
Chinese Journal of Hospital Pharmacy
关键词
瘙痒性皮肤病
利多卡因
卤米松
pruritic skin disorder
lidocaine
halometasone
