摘要
目的:探讨高危型HPV检测联合细胞学检查在宫颈病变筛查中的的意义。方法:选取在笔者所在医院进行宫颈癌筛查检测的女性患者1875例,对所有患者分别进行高危型HPV基因检测(HR-HPV-DNA)、宫颈液基薄层细胞检测(TCT)、HR-HPV-DNA+TCT联合检查,以病理学检验为确诊依据。结果:在不同等级的宫颈病变中,HR-HPV+TCT检查的阳性率不同,宫颈癌前病变(CIN)Ⅰ级患者中为62.12%、CINⅡ患者中77.63%、CINⅢ患者中83.33%、宫颈浸润癌患者中92.31%,总敏感度为97.33%,特异度为71.20%。结论:高危型HPV检测联合细胞学检查应用于宫颈病变筛查中,可以增加筛查的有效率,适用于宫颈癌的早期诊断。
Objective：To investigate the significance of the detection of high-risk HPV combined with cytological examination in cervical lesions screening. Method：1875 cases of female patients,screening for cervical cancer.All of the patients,respectively for HPV type gene detection（HR HPV-DNA）,cervical liquid thin layer cell test（TCT）,HR-HPV DNA＋TCT joint inspection,pathological diagnosis standard for inspection.Result：In different levels of cervical lesions, HR-check out the positive rate of HPV＋TCT was different.CIN Ⅰ patients was 62.12%,CIN Ⅱ patients was 77.63%,CIN Ⅲpatients was 83.33%,92.31%of patients with cervical invasive cancer.The overall sensitivity was 97.33%.Specific degree was 71.20%.Conclusion：High-risk type HPV detection combined cytological examination,used in screening of cervical lesions,can increase the screening efficiency,is suitable for early diagnosis of cervical cancer.
出处
《中外医学研究》
2014年第16期54-55,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
