摘要
目的探讨77例肾移植术后肺部感染患者的临床特点及诊治措施。方法回顾性分析1993-2013年我院呼吸科收治的77例肾移植术后肺部感染患者的临床资料。结果 77例中单一病原体感染33例(43%),两种及以上病原体感染24例(31%),不明病原体感染20例(26%)。其中检出细菌30例,主要有结核分枝杆菌、铜绿假单胞菌、鲍曼不动杆菌、凝固酶阴性葡萄球菌;真菌26例,主要为念珠菌、曲霉菌;病毒24例,主要为巨细胞病毒、流感病毒;卡氏肺孢子菌5例;肺炎支原体3例。治疗上主要给予吸氧、调整免疫抑制剂和糖皮质激素用量、抗感染等治疗,77例中好转65例,恶化2例,死亡10例(10/77,12.99%),死亡原因均为重症肺炎。结论肺部感染是肾移植术后的严重并发症,易导致患者死亡。
Objective To study the clinical features,diagnosis and treatment of pulmonary infection patients after renal transplantation.Methods Clinical data about 77 pulmonary infection patients after renal transplantation admitted to our department from January 1993 to August 2013 were retrospectively analyzed.Results Of the 77 patients,33 （43%） were infected with a single pathogen,24 （31%） with two or more pathogens,and 20 （26%） with unclear pathogens.The bacteria detected in 30 patients were mycobacterium tuberculosis,pseudomonas aeruginosa,acinetobacter baumannii,coagulase negative staphylococci.The fungi detected in 26 patients were candida and aspergillus.The viruses detected in 24 patients were CMV and influenza virus.PCP and mycoplasmal pneumonia were detected in 5 and 3 patients,respectively.The patients received oxygen inhalation therapy,immunosuppressant and glucocorticoid treatment with their dose adjusted,and anti-infection treatment.Of the 77 patients,65 were cured,2 had their condition deteriorated,and 10 died （12.99%）.Severe pneumonia was the cause of death.Conclusion Pulmonary infection is a severe complication of renal transplantation and easy to result in death of patients.
出处
《解放军医学院学报》
CAS
2014年第6期538-540,共3页
Academic Journal of Chinese PLA Medical School
基金
全军医学科技"十二五"科研项目(BWS11J057)~~
关键词
肾移植
肺炎
诊断
治疗
kidney transplantation
pneumonia
diagnosis
therapy
