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腰大池持续引流对防治Chiari畸形Ⅰ型术后并发症的临床疗效观察 被引量：5

Observation of clinical efficacy of lumbar continuous drainage of fluid on prevention and treatment postoperative complications of Chiari malformation typeⅠ
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摘要 目的观察术后第1天预防性应用腰大池持续引流(lumbar continuous drainage of fluid,LCDF)对防治Chiari畸形Ⅰ型(Chiari malformation typeⅠ,CMI)行枕大池重建术后早期并发症的临床疗效。方法选择2012年1-12月解放军总医院神经外科三病区收治的Chiari畸形Ⅰ型患者65例,均行枕大池重建术;按照术后第1天是否预防性应用LCDF随机分为两组,观察组35例,对照组30例,前者行预防性LCDF,后者未行预防性LCDF。术后1周比较两组切口愈合状况、发热例数、脑脊液(cerebrospinal fluid,CSF)白细胞计数、住院天数,应用SPSS13.0统计软件分析数据。结果观察组和对照组各项观察指标比较,发热患者分别为1例和5例;切口愈合不良患者分别为0例和3例,P值分别为0.073及0.083,P>0.05,差异无统计学意义;平均住院天数分别为(8.362±2.256)d和(15.394±1.615)d;CSF白细胞计数比较分别为(6.967±0.552)×106/L和(226.703±9.326)×106/L,P值分别为0.000和0.024,P<0.05,差异有统计学意义。结论 Chiari畸形Ⅰ型患者行枕大池重建术,术后第1天预防性应用LCDF治疗,可缩短住院时间,防治术后脑脊液感染,有一定临床疗效。 Objective To observe the preventive treatment results after cistern magna reconstruction of patients with Chiari malformation type Ⅰ when prophylactic lumbar continuous drainage of fluid （LCDF） was applied in the first postoperation day.Methods Sixty-five cases who were diagnosed as CMI and all underwent cistema magna reconstruction admitted to Neurosurgery Third Department of Chinese PLA General Hospital from January 2012 to December 2012 were randomly selected.According to whether LCDF was applied in the first postoperation day,they were randomly divided into two groups：prophylactic LCDF group （n=35） and observation group （n=30）.The former did prophylactic LCDF,and the latter did not do that.Wound healing situation,the number of fever cases,cerebrospinal fluid （CSF） leukocyte count and length of stay were observed and compared between two groups.Then SPSS 13.0 statistical software was applied to analyze data.Results Compared the observed indicators in two groups,there was no statistically significant difference in number of fever cases and poor wound healing cases （Former∶ 1 and 5 cases; Latter∶ 0 and 3 cases; P =0.073 and 0.083,respectively）,P 〉 0.05; while the average length of hospital stay and CSF leukocyte count had statistically significant difference （Former∶ （8.362 ± 2.256） and （15.394 ± 1.615） days; Latter∶（6.967 ± 0.552） × 106/L and（226.703 ± 9.326） × 106/L ; P=0.000 and 0.024,respectively）,P 〈 0.05.Conclusion There is a certain clinical efficacy if CMI patients underwent cistema magna reconstruction and applied prophylactic LCDF treatment in the first postoperative day,and it also could shorten hospital stay time,prevent and control postoperative CSF infection.
作者 程诚 尚爱加 佟怀宇 张远征 乔广宇
机构地区 解放军总医院神经外科
出处 《解放军医学院学报》 CAS 2014年第6期552-554,584,共4页 Academic Journal of Chinese PLA Medical School
关键词 腰大池持续引流 CHIARI畸形 手术并发症 临床疗效 continuous lumbar drainage chiari malformation operative complications clinical treatment effectiveness
分类号 R742 [医药卫生—神经病学与精神病学]
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共引文献2794

同被引文献63

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解放军医学院学报
2014年 第6期

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