摘要
目的分析高压氧辅助药物治疗动脉粥样硬化脑血管痉挛的效果。方法选择在本院接受住院治疗的动脉粥样硬化脑血管痉挛患者作为研究对象,分别给予单纯药物治疗及高压氧辅助药物治疗,比较有效率、血液学指标、基底动脉管径及NO、NOS、Ca2+含量等。结果观察组有效率(97.06%)、基底动脉管径[(4.98±1.35)mm]、NO[(59.43±11.48)μmol/L]、NOS[(98.43±14.38)kU/L]均明显高于对照组;胆固醇[(3.12±0.72)mmol/L]、甘油三酯[(1.27±0.41)mmol/L]、血小板计数[(112.74±13.36)×109/L]、血黏度[(1.21±0.37)mPa·s]、[Ca2+(17.07±1.65)g/μmol]明显低于对照组(P<0.05)。结论高压氧辅助药物可有效提高动脉粥样硬化脑血管痉挛患者的临床疗效,优化血液学指标,升高基底动脉管径、NO及NOS,减少Ca2+含量,具有积极的临床意义。
Objective To analyze the efficacy of hyperbaric oxygen combined with drug on patients with atherosclerotic cerebral vasospasm. Methods Patients with atherosclerotic cerebral vasospasm admitted to our hospital were chosen as re-search subjects ,and divided into observation group and control group. The control group was given drug therapy alone and the observation group was given hyperbaric oxygen combined with drug therapy. The efficiency of treatment ,hematological index , and basilar artery diameter ,NO ,NOS ,Ca2＋ level of the two groups were compared. Results The efficacy rate （97.06% ） ,basal artery diameter（4.98 ± 4.98） mm ,NO（59.43 ± 11.48）μmol/L ,NO （98.43 ± 14.38） kU/L of observation group were sig-nificantly higher than those of the control group ;Cholesterol（3.12 ± 0.72） mmol/L ,triglycerides（1.27 ± 0.41） mmol/L , platelet count（112.74 ± 13.36）10^9/L ,blood viscosity（1.21 ± 0.37 ）mPa·s ,Ca2＋ （17.07 ± 1.65） g/μmol were significantly lower than those of the control group（P＆lt;0.05）.Conclusion Hyperbaric oxygen aided drug can improve atherosclerosis of cer-ebral vasospasm in patients with clinical efficacy ,optimize haematological indices ,increase basilar artery diameter ,NO and NOS level ,reduce Ca2＋ content with positive clinical significance.
出处
《中国实用神经疾病杂志》
2014年第9期44-45,共2页
Chinese Journal of Practical Nervous Diseases
关键词
动脉粥样硬化
脑血管痉挛
高压氧
血气指标
Atherosclerosis
Cerebral vasospasm
Hyperbaric oxygen
Blood gas index
