摘要
目的探讨甲状腺功能异常对孕妇及妊娠结局的影响。方法回顾性分析2009年3月～2013年10月重庆市万州区第五人民医院待产孕妇的临床资料，按相关标准选择397例甲状腺功能异常的孕妇作为甲异组，选取460例甲状腺功能正常的孕妇作为对照组。入院后进行甲状腺功能相关指标检测，并随访至分娩后2周。比较分析两组孕妇妊娠并发症、不良结局的发生情况。结果甲异组妊娠糖尿病、妊娠高血压和贫血的发生率（15．62％、13．60％、8．82％）明显高于对照组（4．78％、8．04％、5．00％），差异均有统计学意义（P〈0．05）；而甲异组胎盘早剥的发生率（0．76％）与对照组（0．87％）比较，差异无统计学意义（P〉0．05）。甲异组低体重儿、早产儿和流产的发生率（6．05％、4．53％、4．79％）也明显高于对照组（1．96％、1．96％、1．74％），差异均有统计学意义（P〈0．05）；而甲异组胎儿窘迫的发生率（1．26％）与对照组（1．30％）比较，差异无统计学意义（P〉0．05）。结论甲状腺功能异常对孕妇及妊娠结局都有不良影响，只有在最大程度上将孕妇整个孕期的甲状腺功能控制在正常范围内，才能保证孕妇获取良好的妊娠结局。
Objective To discuss the effect of abnormal thyroid function on pregnant women and pregnancy outcome. Methods Clinical data of pregnant women in the Fifth People＇s Hospital of Wanzhou Distric in Chongqing City from March 2009 to October 2013 were retrospective analyzed, 397 pregnant women with abnormal thyroid function were se- lected as the thyroid dysfunction group according to the related standard; then 460 pregnant women with normal thyroid function were selected as control group. Relevant indicators of thyroid function were tested after admission, and were followed up for 2 weeks after delivery. The occurrence of complications and outcomes of pregnant women in two groups were compared analyzed. Results The incidence rates of gestational diabetes, hypertension and anemia pregnancy in thyroid dysfunction group （15.62%, 13.60%, 8.82%） were significantly higher than those of control group （4.78%, 8.04%, 5.00%）, the differences were statistically significant （P 〈 0.05）; but there was no significant difference on the incidence of placental abruption between thyroid dysfunction group （0.76%） and control group （0.87%） （P 〉 0.05）. The incidence rates of low birth weight, premature and abortion in thyroid dysfunction group （6.05%, 4.53%, 4.79%）, also were signif- icantly higher than those of the control group （1.96%, 1.96%, 1.74%）, the differences were statistically significant （P 〈 0.05）; but there was no significant difference on the incidence of fetal distress between thyroid dysfunction group （1.26%） and control group （1.30%） （P 〉 0.05）. Conclusion There are adverse effects of abnormal thyroid function on pregnant women and pregnancy outcome, only control the thyroid function of pregnant women in the normal range max- imum degree throughout pregnancy can ensure that pregnant women get a good outcome of pregnancy.
出处
《中国医药导报》
CAS
2014年第17期139-141,共3页
China Medical Herald
基金
重庆市卫生局医学科学技术研究资助项目(编号2010-3-038)
关键词
甲状腺功能异常
孕妇
妊娠结局
并发症
Abnormal thyroid function
Pregnant women
Pregnancy outcome
Complication
