摘要
目的观察自然流产患者的甲状腺功能状态以及妊娠次数、人工流产次数等对体内激素水平的影响。方法选取2010年4月至2013年6月自然流产患者108例为观察组,另外选取有过正常生育且无不良孕产史的同龄女性108例为对照组,检测对比两组的甲状腺功能状态(TSH、FT3、FT4、TPOAb水平)、各种激素水平,并观察职业、年龄、妊娠次数等因素对体内激素水平的影响,采用秩和检验、方差分析、logistic回归分析等对结果进行统计学分析。结果自然流产患者甲状腺功能状态异常比例高于对照组,两组比较差异有统计学意义(P<0.05或<0.01),logistic回归分析结果提示人工流产次数和妊娠次数对人体激素水平有显著影响。结论及时诊断并治疗甲状腺功能状态异常,减少人工流产次数、妊娠次数在预防自然流产的发生上有重要的意义。
Objective To observe the thyroid function of women with spontaneous abortion and the influence of times of pregnancy and induced abortion on hormone levels.Methods 108 women who sought medical care for sponta- neous abortion during April, 2010 and June, 2013 were recruited as the observation group.Another 108 of women with normal childbirth experience were enrolled as the control group. Then, their thyroid function （TSH, FT3, FT4 and TPOAb levels） and hormone levels were detected and compared. Influence of occupation,age, times of pregnancy and other factors on hormone levels were observed.Statistical methods used in the research included rank sum test, analysis of variance and logistic regression.Results The proportion of abnormal thyroid function in the observation group was higher than that in the control group,so the difference was statistically significant（ P 〈0.05 or 〈0.01）.And the logistic regression result suggested that the number of abortions and pregnancies have significant impact on human hormone levels.Conclusion Prompt diagnosis and treatment of abnormal thyroid function and reducing the number of abortions and pregnancies are significant in the prevention of spontaneous abortion.
出处
《右江医学》
2014年第3期292-295,共4页
Chinese Youjiang Medical Journal
关键词
自然流产
甲状腺功能
激素水平
回归分析
spontaneous abortion
thyroid function
hormone levels
regression analysis
