摘要
目的:观察养阴益气法治疗病毒性心肌炎恢复期的疗效。方法:将符合病毒性心肌炎恢复期纳入标准的110例患者随机分为中药组55例和对照组55例,中药组应用养阴益气中药组方治疗,对照组采用西药治疗。疗程4周,观察治疗前后的主要症状体征(心悸、胸闷、胸痛、气短乏力、头晕、失眠)、血清心肌酶(AST、LDH、CK、CK-MB)、动态心电图变化和中医证候疗效的改善情况。结果:两组治疗后对于病毒性心肌炎恢复期患者的主要症状(如心悸、胸闷、胸痛、气短、乏力、低热、心烦、便秘),降低心肌酶(AST、,LDH,CK,CK-MB)和纠正心电图的异常表现方面,均起到良好的改善作用(P<0.05,0.0 1)。在与西药常规治疗比较也发现,对于心悸、胸闷、胸痛、乏力和便秘的积分,中药组较西药组有明显的降低,具有统计学差异(P<0.05)。主要症状疗效评价中,总有效率中药组优于西药组(P<0.01);总体证候疗效评价中,总有效率中药组优于西药组(P<0.05);中药组对血清心肌酶(LDH,CK)的保护性降低作用,优于西药组(P<0.05)。但在心电图的疗效评价上,两组间无统计学差异(P>0.05)。结论:养阴益气组方治疗病毒性心肌炎恢复期的患者具有较好疗效。
Objective： To observe the curative effect of tonifying method in the treatment of viral myocarditis in recovery period.Methods： 110 cases which met the inclusion criteria of viral myocarditis in recovery period were randomly divided into treatment group（ 55 cases） and control group（ 55 patients）. The treatment group was treated with traditional Chinese medicine and the control group was treated by Western medicine. After 4 weeks treatment,the symptoms（ palpitations,chest tightness,chest pain,shortness of breath,fatigue,dizziness,insomnia） were observed before and after treatment and serum myocardial enzymes（ AST,LDH,CK,CK-MB） were tested to improve the situation of dynamic ECG changes and TCM syndrome effects. Results： After treatment in two groups,myocarditis patients＇ main symptoms（ such as palpitations,chest tightness,chest pain,shortness of breath,fatigue,fever,upset,constipation） were recovered and the myocardial enzyme（ AST,CK,CK-MB,LDH） were reduced and abnormal ECG findings were corrected. There was significant difference（ P 〈 0. 05,P 〈 0. 01）. In comparison with the conventional western medicine treatment for the integral palpitations,chest pain,fatigue and constipation,those of traditional Chinese medicine group were obviously lower than with statistical difference（ P 〈 0. 05）. Evaluation of clinical symptoms and the total effective rate of treatment group were better than those of the control group（ P 〈 0. 01）. Evaluation of general syndrome curative effect and the total effective rate of treatment group were better than those of the control group（ P 〈0. 05）. Traditional Chinese medicine group on serum myocardial enzymes（ LDH,CK） and the protective effect has better than western medicine group（ P 〈 0. 05）. But for the electrocardiogram curative effect evaluation,there was no significant difference between the two groups（ P 〉 0. 05）. Conclusion： Tonifying formula in the treatment of viral myocarditis patients＇ recovery has good curative effect.
出处
《辽宁中医杂志》
CAS
2014年第6期1205-1208,共4页
Liaoning Journal of Traditional Chinese Medicine
关键词
病毒性心肌炎恢复期
养阴益气
中药组方
疗效观察
viral myocarditis in recovery period
nourishing Yin and supplementing Qi
Chinese traditional prescription
curative effect observation
