摘要
目的探讨不同年龄段肺炎支原体感染患儿的临床特点。方法选取2009年2月至2012年12月我院收治的202例肺炎支原体感染的患儿,根据年龄的不同将其分为婴幼儿组、学龄前儿童组、学龄儿童组,比较三组肺炎支原体感染患儿的临床特点。结果婴幼儿组患儿临床特征以咳嗽、咳痰以及喘息为主,分别占80.56%和52.78%,69.44%的患儿肺部听诊可闻及干湿性啰音,肺外表现以胃肠道表现较为多见,发生率为36.11%,77.28%的患儿胸片提示出现支气管肺炎;学龄儿童组76.92%的患儿可出现体温>39℃的表现,仅有28.57%的患儿出现咳嗽、咳痰症状,5.49%的患儿出现喘息,20.88%的患儿出现肺部干湿性啰音,肺外表现以皮损较为常见,发生率为13.19%,而胃肠道表现不甚明显,发生率仅为7.69%,仅有25.27%的患儿胸部X线片提示为支气管肺炎;学龄前儿童组的临床特征介于婴幼儿组与学龄儿童组之间。三组患儿的临床特征、淋巴细胞计数以及血CRP水平等情况比较差异均具有统计学意义(P<0.05)。202例MP感染患儿中有44例出现单份血清MP-IgM≥1:80,以学龄前儿童出现最多,24例,占32%;128例出现双份血清MP-IgM阴性转阳性,婴幼儿组出现28例,占77.78%;30例出现MP-IgM增高至少4倍情况,以学龄儿童出现最多,20例,占21.98%。结论不同年龄段肺炎支原体感染患儿的临床特征各有其不同的特点,主要可能是由于肺部损伤机制的不同所导致。
Objective To investigate the different clinical features of mycoplasma pneumoniae infection in children with different ages. Methods 202 children with mycoplasma pneumoniae infection admitted to our hospital from February 2009 to December 2012 were enrolled and divided into infant group, preschool group and school age group according to the age. The clinical features of mycoplasma pneumoniae infection were compared among three groups. Results In infants group, the clinical features were mainly characterized as coughing, sputum and wheezing, accounting for 80.56%and 52.78%, respectively. Wet and dry rales were auscultated in 69.44%children. Besides, gas-trointestinal manifestations were common to be observed in the children with a rate of 36.11%. 77.28% children showed bronchial pneumonia in Chest X-ray. In school age group, 76.92%children showed a body temperature higher than 39℃. Among the children, only 28.57%with coughing, sputum, 5.49%with wheezing, 20.88%with wet and dry rales were found. The skin lesion was a common manifestation with a rate of 13.19%, while the symptoms of the gas-trointestinal tract with a rate of 7.69%were not obvious. Only 25.27%children were diagnosed as bronchial pneu-monia in chest X-ray. The clinical features of preschool group were between infants and school age group. The dif-ferences in the clinical features, blood lymphocyte count and CRP levels among the three groups were statistically significant （P〈0.05）. Serum MP-IgM level of 1：80 and above was detected in 44 of 202 cases with MP infection, where the preschoolers accounted mostly for 32%of 24 cases. A converting from negative to positive was observed in 128 cases of paired serum MP-IgM, where the infant group accounted for 77.78%of 28 cases, and an increasing of least 4-fold in MP-IgM were found in 30 cases, where the school age group accounted for 21.98%with 20 cases. Conclusion Mycoplasma pneumoniae infection in children with different ages shows different clinical features, which mainly due to different mechanisms in lung injury.
出处
《海南医学》
CAS
2014年第12期1753-1755,共3页
Hainan Medical Journal
关键词
不同年龄段
肺炎支原体感染
临床特点
Different ages
Mycoplasma pneumoniae infection
Clinical features
